78739-32-9Relevant articles and documents
Efficient stereocontrolled synthesis of D-erythro-sphingosine from N-benzoyl-D-glucosamine
Murakami, Teiichi,Hato, Masakatsu
, p. 823 - 827 (2007/10/03)
D-erythro-Sphingosine is synthesized from N-benzoyl-D-glucosamine 2 in a highly regio- and stereo-controlled manner. The key features in the synthesis involve the efficient conversion of compound 2 into the vinyl epoxide 10 and the subsequent SN2′-type reaction with a Grignard reagent in the presence of CuCN to afford the 1-O,2-N-protected sphingosine 11.