78715-83-0 Usage
Description
METHYL (S)-(+)-4 5-DIHYDRO-2-PHENYL-4-, also known as (S)-2-Phenyl-4,5-dihydrooxazole-4-carboxylic Acid Methyl Ester, is a chemical compound that plays a significant role in the synthesis of various organic compounds. It is characterized by its unique structure, which includes an oxazoline ring and a phenyl group, making it a valuable building block in the development of new molecules with potential applications in different industries.
Uses
Used in Pharmaceutical Industry:
METHYL (S)-(+)-4 5-DIHYDRO-2-PHENYL-4is used as a key intermediate in the synthesis of oxazoline-based organocatalysts for [application reason]. These organocatalysts are essential in facilitating various chemical reactions, particularly in the synthesis of pharmaceutical compounds. The unique structure of METHYL (S)-(+)-4 5-DIHYDRO-2-PHENYL-4allows for the development of novel catalysts with improved selectivity and reactivity, leading to more efficient and environmentally friendly synthetic processes.
Used in Chemical Research:
In the field of chemical research, METHYL (S)-(+)-4 5-DIHYDRO-2-PHENYL-4is used as a versatile building block for the development of new molecules with potential applications in various industries. Its unique structure and reactivity make it an attractive candidate for the synthesis of complex organic compounds, including those with potential biological activities or novel materials properties.
Used in Material Science:
METHYL (S)-(+)-4 5-DIHYDRO-2-PHENYL-4is also used in the development of new materials with specific properties, such as improved mechanical strength, thermal stability, or chemical resistance. The incorporation of this compound into the molecular structure of various materials can lead to the creation of innovative products with enhanced performance characteristics, making it a valuable asset in the field of material science.
Check Digit Verification of cas no
The CAS Registry Mumber 78715-83-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,7,1 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 78715-83:
(7*7)+(6*8)+(5*7)+(4*1)+(3*5)+(2*8)+(1*3)=170
170 % 10 = 0
So 78715-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H11NO3/c1-14-11(13)9-7-15-10(12-9)8-5-3-2-4-6-8/h2-6,9H,7H2,1H3/t9-/m0/s1
78715-83-0Relevant articles and documents
A NEW METHOD FOR THE STEREOPECIFIC SYNTHESIS OF ETHER PHOSPHOLIPIDS. PREPARATION OF THE AMIDE ANALOG OF PLATELET ACTIVATING FACTOR AND RELATED DERIVATIVES
Chandrakumar, Nizal S.,Hajdu Joseph
, p. 1043 - 1046 (1982)
A nowel stereopecific synthesis of biologically active ether-phospholipids is reported.
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate
Zhang, Yong-Kang,Plattner, Jacob J.,Easom, Eric E.,Jacobs, Robert T.,Guo, Denghui,Freund, Yvonne R.,Berry, Pamela,Ciaravino, Vic,Erve, John C. L.,Rosenthal, Philip J.,Campo, Brice,Gamo, Francisco-Javier,Sanz, Laura M.,Cao, Jianxin
, p. 5889 - 5908 (2017/07/22)
Carboxamide pyrazinyloxy benzoxaboroles were investigated with the goal to identify a molecule with satisfactory antimalarial activity, physicochemical properties, pharmacokinetic profile, in vivo efficacy, and safety profile. This optimization effort discovered 46, which met our target candidate profile. Compound 46 had excellent activity against cultured Plasmodium falciparum, and in vivo against P. falciparum and P. berghei in infected mice. It exhibited good PK properties in mice, rats, and dogs. It was highly active against the other 11 P. falciparum strains, which are mostly resistant to chloroquine and pyrimethamine. The rapid parasite in vitro reduction and in vivo parasite clearance profile of 46 were similar to those of artemisinin and chloroquine, two rapid-acting antimalarials. It was nongenotoxic in an Ames assay, an in vitro micronucleus assay, and an in vivo rat micronucleus assay when dosed orally up to 2000 mg/kg. The combined properties of this novel benzoxaborole support its progression to preclinical development.
Incorporation and visualization of azido-functionalized: N -oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells
Walter,Collenburg,Japtok,Kleuser,Schneider-Schaulies,Müller,Becam,Schubert-Unkmeir,Kong,Bieberich,Seibel
supporting information, p. 8612 - 8614 (2016/07/13)
The synthesis and biological evaluation of azido-N-oleoyl serinol is reported. It mimicks biofunctional lipid ceramides and has shown to be capable of click reactions for cell membrane imaging in Jurkat and human brain microvascular endothelial cells.
