60040-82-6

Basic information

• Product Name: Benzoic acid,2,2'-(1,2-ethanediyl)bis-, dimethyl ester (9CI)
• Synonyms: o,o'-Ditolyldicarboxylicacid, dimethyl ester (1CI); a,a'-Bi-o-toluic acid, dimethylester (6CI); NSC 404913
• CAS NO: 60040-82-6
• Molecular Formula: C18H18 O4
• Molecular Weight: 298.339
• Mol File: 60040-82-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 424.2°Cat760mmHg
• Flash Point: 210.5°C
• Density: 1.153g/cm³
• CAS DataBase Reference: Benzoic acid,2,2'-(1,2-ethanediyl)bis-, dimethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid,2,2'-(1,2-ethanediyl)bis-, dimethyl ester (9CI)(60040-82-6)
• EPA Substance Registry System: Benzoic acid,2,2'-(1,2-ethanediyl)bis-, dimethyl ester (9CI)(60040-82-6)

Safety Data

• Hazardous Substances Data: 60040-82-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 4281-17-8 2,2'-(ethane-1,2-diyl)bisbenzoic acid 
• 186581-53-3 diazomethane 
• 2417-73-4 methyl 2-bromomethylbenzoate 
• 72872-62-9 o,o'-benzil dicarboxylic acid 
• 694-80-4 2-bromo-1-chlorobenzene 
• 74-88-4 methyl iodide 
• 81447-53-2 7,7-Dimethoxybicyclo<4.2.0>octa-1,3,5-triene 
• 56526-10-4 o,o'-Bis(methoxycarbonyl)stilbene 

Downstream Products

• 97828-97-2 2,2'-bis-(α-bromo-benzhydryl)-bibenzyl 
• 96871-56-6 5,5,6,6-tetraphenyl-5,6,11,12-tetrahydro-dibenzo[a,e]cyclooctene 
• 5668-61-1 2,2'-bis(bromomethyl)bibenzyl 
• 96871-78-2 2,2'-bis-(α-hydroxy-benzhydryl)-bibenzyl 
• 19064-90-5 2-(2-hydroxymethylphenethyl)phenylmethanol 

Relevant articles and documents

Electrochemical reduction of methyl 2-bromomethylbenzoate at carbon cathodes in dimethylformamide containingwater

Cyclic voltammetry and controlled-potential electrolysis have been employed to examine the electrochemical reduction of methyl 2-bromomethylbenzoate at carbon cathodes in dimethylformamide (DMF) containing tetramethylammonium tetrafluoroborate (TMABF4). A cyclic voltammogram for the reduction of the substrate exhibits one irreversible cathodic wave with a peak potential of -1.45 V vs. SCE, which is due to the two-electron cleavage of the benzylic carbon-bromine bond. The corresponding reductive peak current also increases incrementally with the amount of water in DMF. Bulk electrolyses of methyl 2-bromomethylbenzoate have been carried out at -1.85 V vs. SCE with different concentrations of water in the solvent. The reduction process involves carbanion intermediates to afford various products including phthalide, which is generated via intramolecular cyclization that is affected by the presence of water. Detailed mechanism for the electrochemical reaction is proposed and further studied by isotope incorporation experiment.

REDUCTIVE COUPLING OF BENZYL HALIDES USING NICKEL(0)-COMPLEX GENERATED IN SITU IN THE PRESENCE OF TETRAETHYLAMMONIUM IODIDE, A SIMPLE AND CONVENIENT SYNTHESIS OF BIBENZYLS

Zerovalent nickel complex generated in situ by reduction of NiBr2(PPh3)2 with zinc powder in the presence of Et4NI was found to be an effective catalyst for homo-coupling of benzyl halides.The catalytic reactions proceeded smoothly in various solvents under mild conditions to afford dehalogenative-coupling products in good to high yields.