60129-33-1

Basic information

• Product Name: 2-Propenoic acid, 3-cyclopropyl-, (2E)-
• CAS NO: 60129-33-1
• Molecular Formula: C6H8O2
• Molecular Weight: 112.128
• Mol File: 60129-33-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-cyclopropyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-cyclopropyl-, (2E)-(60129-33-1)
• EPA Substance Registry System: 2-Propenoic acid, 3-cyclopropyl-, (2E)-(60129-33-1)

Safety Data

• Hazardous Substances Data: 60129-33-1(Hazardous Substances Data)

Upstream product

• 21014-26-6 ethyl 3-cyclopropaneprop-2-enoate 
• 64-19-7 acetic acid 
• 1489-69-6 Cyclopropanecarboxaldehyde 
• 98272-33-4 methyl 3-cyclopropylacrylate 
• 107940-09-0 (2-methoxy-1-trimethylsilyloxy-vinyloxy)-trimethyl-silane 
• 141-82-2 malonic acid 

Downstream Products

• 189498-31-5 3-((E)-3-cyclopropylpropenoyl)-4-(S)-phenyl-2-oxazolidinone 
• 289725-15-1 N-trans-3-(cyclopropyl)acryloyl-4-(S)-benzyl-2-oxazolidinone 
• 1374419-05-2 (E)-phenyl 3-cyclopropylacrylate 

Relevant articles and documents

Synthesis and pharmacological in vitro investigations of novel shikonin derivatives with a special focus on cyclopropane bearing derivatives

Melanoma is the deadliest form of skin cancer and accounts for about three quarters of all skin cancer deaths. Especially at an advanced stage, its treatment is challenging, and survival rates are very low. In previous studies, we showed that the constitu

TiCl4-mediated olefination of aldehydes with acetic acid and alkyl acetates: A stereoselective approach to (E)-α,β-unsaturated carboxylic acids and esters

A new method has been developed for the preparation of α,β- unsaturated carboxylic acids and corresponding esters with (E)-stereoselectivity via the TiCl4-mediated olefination of aldehydes. The method, which uses readily available acetic acid or its alkyl esters as active methylene partners, is more flexible and complementary to conventional routes in the preparation of (E)-cinnamic acid derivatives.

3-cyclopropyl and 3-cyclobutyl pyrrolidine modulators of chemokine receptor activity

The present invention is directed to pyrrolidine compounds of the formula I: (wherein R1, R2, R3, R4c, R4d, and R4fare defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.