60154-59-8

Basic information

• Product Name: BENZYL(2-CHLOROETHYL)ETHYLAMINE
• Synonyms: BENZYL(2-CHLOROETHYL)ETHYLAMINE
• CAS NO: 60154-59-8
• Molecular Formula: C₁₁H₁₆ClN
• Molecular Weight: 197.70444
• Mol File: 60154-59-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BENZYL(2-CHLOROETHYL)ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL(2-CHLOROETHYL)ETHYLAMINE(60154-59-8)
• EPA Substance Registry System: BENZYL(2-CHLOROETHYL)ETHYLAMINE(60154-59-8)

Safety Data

• Hazardous Substances Data: 60154-59-8(Hazardous Substances Data)

Upstream product

• 91339-47-8 N-benzyl-2-(ethylamino)ethanol 
• 69928-35-4 2-(Benzyl-ethyl-amino)-ethanol; hydrochloride 
• 100-44-7 benzyl chloride 

Downstream Products

• 1096359-57-7 {4-[2-(benzyl-ethyl-amino)-ethoxy]-phenyl}-(2-butyl-benzofuran-3-yl)-methanone 
• 1096359-58-8 {4-[2-(benzyl-ethyl-amino)-ethoxy]-3-iodo-phenyl}-(2-butyl-benzofuran-3-yl)-methanone 
• 1096359-59-9 {4-[2-(benzyl-ethyl-amino)-ethoxy]-3,5-diiodo-phenyl}-(2-butyl-benzofuran-3-yl)-methanone 

Relevant articles and documents

Trace amine-associated receptor 1 (TAAR1) is activated by amiodarone metabolites

Amiodarone (Cordarone, Wyeth-Ayerst Pharmaceuticals) is a clinically available drug used to treat a wide variety of cardiac arrhythmias. We report here the synthesis and characterization of a panel of potential amiodarone metabolites that have significant structural similarity to thyroid hormone and its metabolites the iodothyronamines. Several of these amiodarone derivatives act as specific agonists of the G protein-coupled receptor (GPCR) trace amine-associated receptor 1 (TAAR1). This result demonstrates a novel molecular target for amiodarone derivatives with potential clinical significance.