60173-64-0 Usage
Description
Benzenamine, N-(1,1-dimethyl-2-propenyl)-, also known as N-1,1-Dimethylallyl-aniline, is an organic compound that serves as an intermediate in the synthesis of various compounds. It is characterized by the presence of an amine group attached to a benzene ring, with a 1,1-dimethyl-2-propenyl group as a substituent. This unique structure endows it with potential applications in different industries.
Uses
Used in Pharmaceutical Industry:
Benzenamine, N-(1,1-dimethyl-2-propenyl)is used as an intermediate in the synthesis of Endophenazine A, a novel phenazine antibiotic. This antibiotic exhibits antimicrobial activities against Gram-positive bacteria and some filamentous fungi, making it a valuable compound in the development of new antimicrobial agents to combat drug-resistant infections.
Used in Agricultural Industry:
In addition to its pharmaceutical applications, Benzenamine, N-(1,1-dimethyl-2-propenyl)is also utilized as an intermediate in the synthesis of herbicides. Specifically, it plays a role in the production of compounds with herbicidal activity against Lemna minor, commonly known as duckweed. This application highlights its potential use in developing effective and targeted herbicides for controlling unwanted plant growth in agricultural settings.
Check Digit Verification of cas no
The CAS Registry Mumber 60173-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,7 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 60173-64:
(7*6)+(6*0)+(5*1)+(4*7)+(3*3)+(2*6)+(1*4)=100
100 % 10 = 0
So 60173-64-0 is a valid CAS Registry Number.
60173-64-0Relevant articles and documents
The first synthesis of 7-prenylisatin
Liang, Dawei,Wang, Yueqiu
, p. 172 - 173 (2019/04/25)
The first synthesis of 7-prenylisatin, an isatin-type antibiotic with prominent activity against Bacillus subtilis, has been accomplished in 16% overall yield from 2-methylbut-3-en-2-ol and aniline via a five-step procedure. The protocol includes the arom
Iron-Catalyzed Intramolecular Aminations of C(sp3)?H Bonds in Alkylaryl Azides
Alt, Isabel T.,Guttroff, Claudia,Plietker, Bernd
supporting information, p. 10582 - 10586 (2017/08/22)
The nucleophilic iron complex Bu4N[Fe(CO)3(NO)] (TBA[Fe]) catalyzes the direct intramolecular amination of unactivated C(sp3)?H bonds in alkylaryl azides, which results in the formation of substituted indoline and tetrahydroquinoline derivatives.
Achieving control over the branched/linear selectivity in palladium-catalyzed allylic amination
Dubovyk, Igor,Watson, Iain D. G.,Yudin, Andrei K.
, p. 1559 - 1575 (2013/03/28)
Palladium-catalyzed reaction of unsymmetrical allylic electrophiles with amines gives rise to regioisomeric allylic amines. We have found that linear products result from the thermodynamically controlled isomerization of the initially formed branched products. The isomerization is promoted by protic acid and active palladium catalyst. The use of base shuts down the isomerization pathway and allows for the preparation and isolation of branched allylic amines. Solvent plays a key role in achieving high kinetic regioselectivity and in controlling the rate of isomerization. The isomerization can be combined with ring-closing metathesis to afford the synthesis of exocyclic allylic amines from their endocyclic precursors.
