60214-04-2

Basic information

• Product Name: ethyl 2-(2-benzoylhydrazineyl)-2-oxoacetate
• Synonyms: ethyl 2-(2-benzoylhydrazineyl)-2-oxoacetate
• CAS NO: 60214-04-2
• Molecular Weight: 236.227
• Mol File: 60214-04-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: ethyl 2-(2-benzoylhydrazineyl)-2-oxoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(2-benzoylhydrazineyl)-2-oxoacetate(60214-04-2)
• EPA Substance Registry System: ethyl 2-(2-benzoylhydrazineyl)-2-oxoacetate(60214-04-2)

Safety Data

• Hazardous Substances Data: 60214-04-2(Hazardous Substances Data)

Upstream product

• 613-94-5 benzoic acid hydrazide 
• 4755-77-5 Ethyl oxalyl chloride 
• 35196-48-6 ethyl 2-hydrazino-2-oxoacetate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 98591-60-7 5-phenyl-1,3,4-oxadiazole-2-carbonyl chloride 
• 99066-76-9 5-phenyl-1,3,4-oxadiazole-2-carboxylic acid 
• 103028-60-0 phenyl-[1,3,4]thiadiazole-2-carboxylic acid 

Relevant articles and documents

One-Pot Synthesis of Decahydropyrene via Tandem C-H Activation/Intramolecular Diels-Alder/1,3-Dipolar Cycloaddition

A novel decahydropyrene synthesis has been successfully developed involving a tandem rhodium-catalyzed C-H activation/intramolecular Diels-Alder reaction/1,3-dipolar cycloaddition cascade process by using diazole as a traceless directing group. The advantage of this one-pot strategy is a quite simple, efficient, highly stereoselective, and unique product structure.

PYRIDAZINONE COMPOUNDS AND USES THEREOF

Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.

Intramolecular cycloadditions of photogenerated azaxylylenes with oxadiazoles provide direct access to versatile polyheterocyclic ketopiperazines containing a spiro-oxirane moiety

Photogenerated azaxylylenes undergo intramolecular cycloadditions to 1,3,4-oxadiazole pendants, which are accompanied by concomitant release of dinitrogen, yielding functionalized ketopiperazinoquinolinols containing an oxirane moiety fused to the quinolinole moiety while spiro-connected to diketopiperazine. These primary photoproducts are reactive versatile intermediates which can be further derivatized under nucleophilic SN1- or SN2-like ring opening of the oxirane moiety. The oxidized quinolinones undergo new rearrangements under the conditions of the Schmidt reaction, leading to unprecedented triazacanoindolinones.