60491-95-4

Basic information

• Product Name: 3-BROMO-4,4-DIMETHYL-2-OXAZOLIDINONE
• Synonyms: 3-BROMO-4,4-DIMETHYL-2-OXAZOLIDINONE;2-Oxazolidinone, 3-bromo-4,4-dimethyl-;3-bromo-4,4-dimethyloxazolidin-2-one;NBDMO;Einecs 262-261-9
• CAS NO: 60491-95-4
• Molecular Formula: C₅H₈BrNO₂
• Molecular Weight: 194.02652
• EINECS: 262-261-9
• Mol File: 60491-95-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 117-119 °C
• Boiling Point: 169.4°C at 760 mmHg
• Flash Point: 56.2°C
• Appearance: /
• Density: 1.615g/cm³
• Vapor Pressure: 1.55mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: 3-BROMO-4,4-DIMETHYL-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4,4-DIMETHYL-2-OXAZOLIDINONE(60491-95-4)
• EPA Substance Registry System: 3-BROMO-4,4-DIMETHYL-2-OXAZOLIDINONE(60491-95-4)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 60491-95-4(Hazardous Substances Data)

Usage

General Description

3-Bromo-4,4-dimethyl-2-oxazolidinone is a chemical compound with the molecular formula C5H9BrNO2. It is a white to off-white crystalline powder that is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also known by its trade name Brodixolone. 3-BROMO-4,4-DIMETHYL-2-OXAZOLIDINONE is classified as an oxazolidinone, which is a type of heterocyclic organic compound. It is primarily used as a building block in organic synthesis, and its versatility makes it a valuable tool for the production of a wide range of important chemical products. Additionally, it has applications in research and development, particularly in the pharmaceutical industry for the production of potential new drugs.

InChI:InChI=1/C5H8BrNO2/c1-5(2)3-9-4(8)7(5)6/h3H2,1-2H3

Upstream product

• 26654-39-7 4,4-dimethyl-1,3-oxazolidin-2-one 

Downstream Products

• 82760-88-1 3-(2-Bromo-2-phenyl-ethyl)-4,4-dimethyl-oxazolidin-2-one 
• 478918-54-6 3-[(1Z)-2-phenylprop-1-en-1-yl]-1,3-oxazolidin-2-one 
• 82760-89-2 3-(2-Hydroxy-2-phenyl-ethyl)-4,4-dimethyl-oxazolidin-2-one 
• 2953-37-9 3β,5-dihydroxy-5α-cholestan-6-one 
• 1253-84-5 cholestanetriol 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF ORGANIC BROMIDES

The present invention provides a process for the preparation of organic bromides, by a radical bromodecarboxylation of carboxylic acids with a bromoisocyanurate.

Brominating and oxidizing agent and method of using same

There is provided a brominating and oxidizing agent of the formula: STR1 wherein R1, R2, R3 and R4 which may be the same or different, represents a member selected from the group consisting of a hydrogen atom, a C1 -C22 straight or branched alkyl group, a phenyl group, and a substituted phenyl group whose substituents are selected from the group consisting of a methoxy group, a nitro group, a cyano group, a halogen atom (Br, Cl, I), a C1 -C2 dialkylamino group, a C1 -C2 dialkylaminomethyl group, a C1 -C2 dialkylaminoethyl group, a C1 -C2 dialkylammoniummethyl group, a C1 -C2 dialkylammoniumethyl group, a C1 -C2 trialkylammoniummethyl group, a C1 -C2 trialkylammoniumethyl group, a COOR5 group, and a CON(R5)2 group, wherein R5 represents a C1 -C8 straight or branched alkyl group. The compounds falling within formula (I) find wide application as brominating and oxidizing agents in a number of organic reactions in which the prior art compound, N-bromosuccinimide has been employed to date. In comparison to N-bromosuccinimide, the compounds of the instant invention are characterized as being extremely stable to degradation and less polar with respect to their N-Br bond than N-bromosuccinimide such that promotion of "radical" bromine release is achieved with minimal positive bromine release.