60526-81-0Relevant articles and documents
METHODS AND COMPOSITIONS RELATING TO ULTRAPURE 5-(1,1-DIMETHYLHEPTYL)-RESORCINOL
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Page/Page column 29; 30; 34, (2019/05/10)
The invention provides methods and compositions relating to an ultrapure formulation of 5-(1,1-dimethylheptyl)-resorcinol (ultrapure DMHR). The invention features methods for making ultrapure DMHR, including methods that minimize the production of unwanted side products (e.g., the production of homologous alkyl-chain impurities). The invention also features methods of making cannabinoids, such as (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyl-2-octanyl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene-9-carboxylic acid (ajulemic acid), using ultrapure DMHR, including methods that minimize the production of unwanted side products (e.g., the production of homologous alkyl-chain impurities) in the resulting cannabinoid preparation.
Expedient synthesis of potent cannabinoid receptor agonist (-)-CP55,940
Itagaki, Noriaki,Sugahara, Tsutomu,Iwabuchi, Yoshiharu
, p. 4181 - 4183 (2007/10/03)
(Chemical Equation Presented) A stereocontrolled synthesis of (-)-CP55,940, a potent cannabinoid receptor agonist, has been attained using a novel aldolization/retroaldolization interconversion strategy, in which a temporarily generated chiral aldol motif plays essential roles.
Synthesis of functionalized cannabinoids
Harrington, Paul E.,Stergiades, Ioanna A.,Erickson, Joy,Makriyannis, Alexandros,Tius, Marcus A.
, p. 6576 - 6582 (2007/10/03)
An effective synthesis of tricyclic, nonclassical cannabinoids has been developed on the basis of a cation-olefin cyclization that forms the two nonaromatic rings with the desired stereochemistry in a single step.