60557-39-3Relevant articles and documents
Prodrugs of Doxorubicin and Melphalan and Their Activation by a Monoclonal Antibody-Penicillin-G Amidase Conjugate
Vrudhula, Vivekananda M.,Senter, Peter D.,Fischer, Keith J.,Wallace, Philip M.
, p. 919 - 923 (2007/10/02)
The syntheses and cytotoxic activities of substituted N-phenylacetamido derivatives of doxorubicin and melphalan are described.The derivatives were designed as prodrugs which could be activated in a site-specific manner by monoclonal antibody-penicillin-G