60561-17-3 Usage
Description
Sufentanil Citrate, a potent derivative of Fentanyl, is a short-acting synthetic opioid analgesic. It is most commonly used for pain relief during medical operations and is known for its rapid onset and short duration of action. As a controlled substance, it is subject to strict regulations due to its potential for abuse and addiction. Sufentanil Citrate is a crystalline solid and is sold under the trade name Sufenta.
Uses
Used in Medical Operations:
Sufentanil Citrate is used as an analgesic (narcotic) for pain relief during medical operations. Its rapid onset and short duration make it an ideal choice for surgical procedures where precise control of pain management is required.
Used in Clinical Toxicology:
Sufentanil Citrate is utilized as a solution standard in clinical toxicology. It is applicable for use in the analysis of pain prescription monitoring or forensic analysis by techniques such as LC-MS/MS or GC/MS, helping to ensure the accurate measurement and monitoring of this potent opioid.
Used in Pain Management:
As a potent opioid analgesic, Sufentanil Citrate is used for the management of severe pain, particularly in cases where other pain relief options may not be as effective. Its controlled release and short-acting nature make it a valuable tool in the treatment of acute and chronic pain conditions.
Clinical Use
Addition of the 4-methoxymethyl group and bioisosteric replacement of the phenyl with a 2-thiophenyl on the fentanyl structure results in a 10-fold increase in μ opioid activity.
The resultant compound, sufentanil, is 600 to 800 times more potent than morphine. Despite its
greater sedative and analgesic potency, sufentanil produces less respiratory depression at
effective anesthetic doses. Sufentanil is available in an intravenous dosage form, and it is used for
anesthetic procedures. It has a faster onset and shorter duration of action than fentanyl. The short
duration is caused by redistribution from brain tissues after intravenous dosage.
Veterinary Drugs and Treatments
An opioid analgesic, sufentanil may be useful as an anesthesia adjunct
or as an epidural analgesic. In humans, it has been used as the
primary anesthetic in intubated patients with assisted ventilation,
and as a post-operative analgesic.
Check Digit Verification of cas no
The CAS Registry Mumber 60561-17-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,6 and 1 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60561-17:
(7*6)+(6*0)+(5*5)+(4*6)+(3*1)+(2*1)+(1*7)=103
103 % 10 = 3
So 60561-17-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H30N2O2S.C6H8O7/c1-3-21(25)24(19-8-5-4-6-9-19)22(18-26-2)12-15-23(16-13-22)14-11-20-10-7-17-27-20;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-10,17H,3,11-16,18H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
60561-17-3Relevant articles and documents
Preparation method of alfentanil and sufentan and compounds used for preparation of sufentanil and alfentan
-
Paragraph 0266; 0267; 0268, (2017/06/02)
The invention discloses a preparation method of alfentanil and sufentan and compounds used for preparation of sufentanil and alfentan. Specifically, the method for preparation of a compound shown as formula V includes: carrying out BOC reaction on a compound shown as formula IV to obtain the compound shown as formula V in the specification. The method can conveniently, efficiently and safely prepare an intermediate product for synthesis of alfentanil and sufentan, i.e. the compound shown as formula V. And then, the compound shown as formula V can be effectively used for preparation of alfentanil and sufentan.
SUBSTITUTED 4-AMINO-PIPERIDINES
-
Page/Page column 27, (2010/02/17)
The present invention relates to new substituted 4-amino-piperidine opioid receptor modulators, pharmaceutical compositions thereof, and methods of use thereof
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.