60566-42-9

Basic information

• Product Name: L-Leucine, L-phenylalanyl-, ethyl ester
• CAS NO: 60566-42-9
• Molecular Formula: C17H26N2O3
• Molecular Weight: 306.405
• Mol File: 60566-42-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: L-Leucine, L-phenylalanyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, L-phenylalanyl-, ethyl ester(60566-42-9)
• EPA Substance Registry System: L-Leucine, L-phenylalanyl-, ethyl ester(60566-42-9)

Safety Data

• Hazardous Substances Data: 60566-42-9(Hazardous Substances Data)

Upstream product

• 58889-73-9 (S)-N-benzyloxycarbonyl-leucine ethyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 2743-40-0 L-leucine ethyl ester hydrochloride 
• 1161-13-3 N-Cbz-L-Phe 
• 2953-42-6 Z-phenylalanylleucine ethyl ester 
• 85208-90-8 N-(tert-butoxycarbonyl)-L-phenylalanyl-L-leucine ethyl ester 

Downstream Products

• 90819-34-4 glycyl-L-phenylalanyl-L-leucine ethyl ester 
• 3354-31-2 (3S,6S)-3-benzyl-6-isobutylpiperazine-2,5-dione 
• 85208-91-9 N-(tert-butoxycarbonyl)glycyl-L-phenylalanyl-L-leucine ethyl ester 

Relevant articles and documents

Tandem deprotection/coupling for peptide synthesis in water at room temperature

A tandem deprotection/coupling sequence is reported for solution-phase peptide synthesis in water under micellar catalysis conditions using the designer surfactant TPGS-750-M. Cbz deprotection followed by peptide coupling in the presence of COMU and 2,6-lutidine afforded polypeptides containing up to 10 amino acid residues. A broad scope characterizes this new technology. No epimerization has been detected. The associated E Factors, as a measure of "greenness" and known to be extremely high for peptide couplings, have been reduced to less than 10 due to the step-economy and minimal amounts of organic solvent needed for product extraction.

Cyclo(dipeptide) as Low-molecular-mass Gelling Agents to Harden Organic Fluids

Cyclic dipeptides consisting of diverse amino acids can cause physical gelation in a wide variety of organic fluids, including edible oils, glyceryl esters, alcohols and aromatic molecules; the gelation phenomenon is characterized by minimum gel concentration, FTIR spectroscopy, transmission electron microscopy, and X-ray diffraction.

Synthesis of peptide-morphinans based on Diels-Alder adducts of thebaine with enkephalin moieties (Chemistry of opium alkaloids, Part XVI)

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