6059-17-2

Basic information

• Product Name: 4-AMINO-2-HYDROXYBENZOIC ACID ETHYL ESTER
• Synonyms: 4-AMINO-2-HYDROXYBENZOIC ACID ETHYL ESTER;4-Aminosalicylic acid ethyl ester;PAS ethyl ester;Benzoic acid, 4-aMino-2-hydroxy-, ethyl ester
• CAS NO: 6059-17-2
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.19
• Product Categories: Aromatic Esters
• Mol File: 6059-17-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 113 °C
• Boiling Point: 339.2°C at 760 mmHg
• Flash Point: 158.9°C
• Appearance: /
• Density: 1.253g/cm³
• Vapor Pressure: 4.76E-05mmHg at 25°C
• Refractive Index: 1.589
• PKA: 9.98±0.10(Predicted)
• CAS DataBase Reference: 4-AMINO-2-HYDROXYBENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-2-HYDROXYBENZOIC ACID ETHYL ESTER(6059-17-2)
• EPA Substance Registry System: 4-AMINO-2-HYDROXYBENZOIC ACID ETHYL ESTER(6059-17-2)

Safety Data

• Hazardous Substances Data: 6059-17-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H11NO3/c1-2-13-9(12)7-4-3-6(10)5-8(7)11/h3-5,11H,2,10H2,1H3

Upstream product

• 78987-51-6 2-hydroxy-4-nitro-benzoic acid ethyl ester 
• 64-17-5 ethanol 
• 65-49-6 4-Aminosalicylic acid 
• 619-19-2 2-hydroxy-4-nitrobenzoic acid 
• 39614-82-9 2-hydroxy-4-nitrobenzoyl chloride 

Downstream Products

• 110462-20-9 2,2'-dihydroxy-4,4'-methanediyldiamino-di-benzoic acid diethyl ester 
• 91193-67-8 4-(2,2-dichloro-acetylamino)-2-hydroxy-benzoic acid ethyl ester 
• 860510-11-8 2-hydroxy-4-(2-hydroxy-4-nitro-benzoylamino)-benzoic acid ethyl ester 
• 32477-12-6 2-hydroxy-4-nicotinoylamino-benzoic acid ethyl ester 
• 6946-29-8 4-aminosalicylic acid hydrazide 
• 730977-57-8 ethyl 2-hydroxy-4-iodobenzoate 
• 84313-71-3 4-ethoxycarbonylamino-2-hydroxy-benzoic acid ethyl ester 
• 121970-39-6 2-hydroxy-4-[N'-(tri-O-acetyl-2-acetylamino-2-deoxy-β-D-glucopyranosyl)-thioureido]-benzoic acid ethyl ester 
• 22776-13-2 ethyl 4-acetylamino-o-hydroxybenzoate 
• 54012-76-9 10-{[N'-(4-amino-2-hydroxy-benzoyl)-hydrazino]-acetyl}-10H-phenothiazine 
• 79340-64-0 4-(2,7-Dimethyl-quinolin-4-ylamino)-2-hydroxy-benzoic acid ethyl ester; hydrochloride 
• 79340-66-2 4-(2,6-Dimethyl-quinolin-4-ylamino)-2-hydroxy-benzoic acid ethyl ester; hydrochloride 
• 79340-65-1 4-(6-Chloro-2-methyl-quinolin-4-ylamino)-2-hydroxy-benzoic acid ethyl ester; hydrochloride 
• 79340-73-1 4-(7-Chloro-2-methyl-quinolin-4-ylamino)-2-hydroxy-benzoic acid ethyl ester; hydrochloride 

Relevant articles and documents

Synthesis and anti-mycobacterial activity of 4-(4-phenyl-1H-1,2,3-triazol-1-yl)salicylhydrazones: revitalizing an old drug

The antitubercular drug; para-aminosalicylic acid (PAS) was used as the core scaffold for the design of a series of 1H-1,2,3-triazolylsalicylhydrazones upon coupling with triazole and arylhydrazone moietis to furnish a single molecular architecture. The o

P-aminosalicylic acid fluoroquinolone derivative as well as intermediate, preparation method and application thereof

The invention discloses a p-aminosalicylic acid fluoroquinolone derivative and an intermediate, a preparation method and application thereof, and belongs to the technical field of drug synthesis. Thestructural formula of the p-aminosalicylic acid fluoroquinolone derivative is shown in the specification. In-vitro activity determination results show that part of fluoroquinolone aminosalicylate derivatives (compounds for short) and intermediates have inhibition effects on mycobacterium smegmatis; the compounds and intermediates have good inhibition activity on common pathogenic bacteria as a whole; most compounds and intermediates have better antibacterial activity on pichia pastoris as a whole; part of the compounds have good inhibitory activity on citrus canker pathogens. The p-aminosalicylic acid fluoroquinolone derivative and the intermediate thereof have potential application prospects in the fields of tuberculosis resistance, bacteria resistance, fungus resistance and citrus pathogen resistance.

P-aminosalicylic acid dihydroartemisinin derivative as well as preparation method and application thereof

The invention discloses a p-aminosalicylic acid dihydroartemisinin derivative as well as a preparation method and application thereof, and belongs to the technical field of drug synthesis. The structural formula of the p-aminosalicylic acid dihydroartemis