60770-66-3

Basic information

• Product Name: Benzofuran, 5-fluoro-2-methyl-
• Synonyms: Benzofuran, 5-fluoro-2-methyl-
• CAS NO: 60770-66-3
• Molecular Formula: C9H7FO
• Molecular Weight: 150.15
• Mol File: 60770-66-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzofuran, 5-fluoro-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran, 5-fluoro-2-methyl-(60770-66-3)
• EPA Substance Registry System: Benzofuran, 5-fluoro-2-methyl-(60770-66-3)

Safety Data

• Hazardous Substances Data: 60770-66-3(Hazardous Substances Data)

Upstream product

• 128104-95-0 3-(4-fluorophenoxy)-2-chloro-1-propene 
• 128104-96-1 2-(2-chloro-1-propen-3-yl)-4-fluorophenol 
• 1620151-29-2 C₁₄H₁₃FN₂O₃S 
• 496-69-5 2-bromo-4-fluoro-phenol 
• 371-41-5 4-Fluorophenol 
• 59769-37-8 2-(4-Fluorophenoxy)-acetaldehyde Diethyl Acetal 
• 24410-59-1 5-Fluoro[b]benzofuran 
• 74-88-4 methyl iodide 

Downstream Products

• 139313-91-0 (5-Fluoro-benzofuran-2-yl)-acetonitrile 

Relevant articles and documents

Enantio- and Diastereoselective, Complete Hydrogenation of Benzofurans by Cascade Catalysis

We report an enantio- and diastereoselective, complete hydrogenation of multiply substituted benzofurans in a one-pot cascade catalysis. The developed protocol facilitates the controlled installation of up to six new defined stereocenters and produces architecturally complex octahydrobenzofurans, prevalent in many bioactive molecules. A unique match of a chiral homogeneous ruthenium-N-heterocyclic carbene complex and an in situ activated rhodium catalyst from a complex precursor act in sequence to enable the presented process.

Direct Synthesis of 2-Methylbenzofurans from Calcium Carbide and Salicylaldehyde p -Tosylhydrazones

A new methodology for the construction of methyl-substituted benzofuran rings from the reactions of calcium carbide with salicylaldehyde p-tosylhydrazones/2-hydroxyacetophenone p-tosylhydrazones is described. Various 2-methylbenzofurans and 2,3-dimethylbenzofurans could be obtained in satisfactory yield by using a cuprous chloride catalyst. The advantages of this protocol include the use of a readily available and easy-to-handle acetylene source and simple workup procedure.

Hypoglycemic imidazoline compounds

This invention relates to certain novel imidazoline compounds and analogues thereof, to their use for the treatment of diabetes, diabetic complications, metabolic disorders, or related diseases where impaired glucose disposal is present, to pharmaceutical compositions comprising them, and to processes for their preparation.