608-36-6

Basic information

• Product Name: meso-2,3-Dibromosuccinic acid
• Synonyms: meso-2,3-Dibromosuccinicacid,98%;meso-2,3-Dibromosuccinic acid;MESO-2,3-Dibromosuccinic acid ,99%;2,3-dibroMosuccinate;Meso-2,3-DibroMosuccini;Butanedioic acid, 2,3-dibroMo-,(2R,3S)-rel-;2,3-DibroM succinic acid;Meso-2,3-DibroMosuccinic acid 98%
• CAS NO: 608-36-6
• Molecular Formula: C₄H₄Br₂O₄
• Molecular Weight: 275.88
• EINECS: 208-396-9
• Product Categories: Carboxylic Acid Monomers;Monomers;Polymer Science
• Mol File: 608-36-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 288-290 °C(lit.)
• Boiling Point: 262.4 °C at 760 mmHg
• Flash Point: 112.5 °C
• Appearance: White to pale yellow to beige/Powder
• Density: 2.486 g/cm³
• Vapor Pressure: 0.00323mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: 20 g/L (17°C)
• PKA: pK1:1.51;pK2:2.71 (20°C)
• Water Solubility: 20 g/L (17 ºC)
• Merck: 14,3029
• BRN: 1725173
• CAS DataBase Reference: meso-2,3-Dibromosuccinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: meso-2,3-Dibromosuccinic acid(608-36-6)
• EPA Substance Registry System: meso-2,3-Dibromosuccinic acid(608-36-6)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34-36/37/38
• Safety Statements: 26-36/37/39-45-24/25
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 608-36-6(Hazardous Substances Data)

Usage

Chemical Properties

white to pale yellow-beige powder

Uses

meso-2,3-dibromosuccinic acid is used in organic synthesis & pharmaceutical intermediate.

Purification Methods

Crystallise the acid from distilled water, keeping the temperature below 70o. [Beilstein 2 IV 1930.]

InChI:InChI=1/C4H4Br2O4/c5-1(3(7)8)2(6)4(9)10/h1-2H,(H,7,8)(H,9,10)/p-2/t1-,2+

Upstream product

• 110-17-8 (2E)-but-2-enedioic acid 
• 45669-18-9 1,2-Dibromosuccinic anhydride 
• 7732-18-5 water 
• 948907-33-3 (2R,3R)-2,3-diaminosuccinic acid 
• 921-52-8 racem.-2,3-diamino-succinic acid 
• 1113-59-3 bromopyruvic acid 
• 6915-18-0 2-butenedioic acid 
• 108-31-6 maleic anhydride 
• 5926-51-2 bromomaleic anhydride 
• 584-99-6 trans-2-bromobutenedioic acid 
• 644-80-4 cis-2-bromobutenedioic acid 
• 23220-52-2 (2S,3R)-3-aminoaspartic acid 
• 110-15-6 succinic acid 
• 78209-71-9 dibromosuccinic acid 

Downstream Products

• 644-80-4 cis-2-bromobutenedioic acid 
• 110-17-8 (2E)-but-2-enedioic acid 
• 584-99-6 trans-2-bromobutenedioic acid 
• 5926-51-2 bromomaleic anhydride 
• 506-96-7 Acetyl bromide 
• 64-19-7 acetic acid 
• 102457-84-1 meso-2,3-bis-(benzyl-methyl-amino)-succinic acid 
• 66221-33-8 N,N'-diallyl-mesodiaminosuccinic acid 
• 53079-45-1 racem-2,3-bis-benzylamino-succinic acid 
• 14464-17-6 N,N-dibenzyl-aspartic acid 
• 88393-56-0 N,N'-dibenzyltartramide 
• 55645-40-4 (2R,3S)-2,3-bis(benzylamino)succinic acid 
• 384-50-9 meso-2,3-dibromo-1,1,1,4,4,4-hexafluoro-butane 
• 51575-86-1 dimethyl 2,3-dibromobutane-1,4-dicarboxylate 

Relevant articles and documents

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Method of treating DBA mother liquor

The present invention relates to a method of treating a DBA mother liquor, wherein a small amount of a reagent is used, high DBA yield is provided, and waste is less.

Preparation method of 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid

The invention relates to a preparation method of 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid, comprising the steps of subjecting fumaric acid, bromine and hydrobromic acid to additive reaction to generate meso-2,3-dDibromosuccinic acid, subjecting the meso-2,3-dDibromosuccinic acid, benzylamine and a strong base to aminating reaction to generate dibenzylamino salt, subjecting the dibenzylamino salt and triphosgene to cyclization to generate the 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid. The fumaric acid is subjected to addition, and then substitution and cyclization are performed to obtain the 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid, and detection shows that HPLC (high-performance liquid chromatography) content of the 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid may reach 98-99%. The preparation method has the advantages that hydrobromic acid is added for bromination additive reaction, the concentration and reaction temperature of the hydrobromic acid are optimized, and bromine loss is more reduced; amination mother liquid is used in amination, the cost is saved, and product yield is increased; in ring-closure reaction, pH and reaction product concentration are decreased, the yield of the 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid is increased greatly, and the quality of the 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid is improved; experiments verify that through process innovation, production cost is reduced greatly, production efficiency is improved, and the process is energy efficient and environmentally friendly.