60902-27-4 Usage
Description
Phenacetin-d3 is a deuterated analogue of Phenacetin, which is an analgesic and antipyretic agent. It is commonly used as a component in various analgesic mixtures, such as APC tablets, which also contain aspirin and caffeine. Although Phenacetin has been associated with potential carcinogenic effects, Phenacetin-d3 serves as a valuable research tool in the study of its properties and applications.
Uses
Used in Pharmaceutical Research:
Phenacetin-d3 is used as a research compound for investigating the pharmacological properties and potential health risks associated with Phenacetin. Its deuterated nature allows for the study of metabolic pathways, drug interactions, and the development of safer alternatives to Phenacetin.
Used in Analytical Chemistry:
Phenacetin-d3 is employed as an internal standard in analytical chemistry, particularly in the quantification of Phenacetin and related compounds in biological samples. The use of deuterated analogues helps to improve the accuracy and precision of analytical measurements by providing a stable reference point for comparison.
Used in Toxicology Studies:
Phenacetin-d3 is utilized in toxicology research to better understand the mechanisms of action and potential carcinogenic effects of Phenacetin. By comparing the behavior of Phenacetin-d3 with its non-deuterated counterpart, researchers can gain insights into the factors contributing to its toxicity and develop strategies to mitigate these risks.
Used in Drug Development:
Phenacetin-d3 serves as a valuable tool in the development of new drugs with improved safety profiles. By studying the structural and functional differences between Phenacetin and its deuterated analogue, researchers can identify potential modifications that may reduce the risk of adverse effects while maintaining therapeutic efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 60902-27-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,9,0 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60902-27:
(7*6)+(6*0)+(5*9)+(4*0)+(3*2)+(2*2)+(1*7)=104
104 % 10 = 4
So 60902-27-4 is a valid CAS Registry Number.
60902-27-4Relevant articles and documents
Preparation of labeled human drugmetabolites and drug-drug interaction-probes with fungal peroxygenases
Poraj-Kobielska, Marzena,Atzrodt, Jens,Holla, Wolfgang,Sandvoss, Martin,Groebe, Glenn,Scheibner, Katrin,Hofrichter, Martin
, p. 513 - 519 (2014/03/21)
Enzymatic conversion of a drug can be an efficient alternative for the preparation of a complex metabolite compared with a multi-step chemical synthesis approach. Limitations exist for chemical methods for direct oxygen incorporation into organic molecule
