60902-28-5 Usage
Description
ACETAMINOPHEN-D3, also known as Acetaminophen-D3, is a deuterated analog of the widely used analgesic and antipyretic drug Acetaminophen. It is a white solid with chemical properties that make it suitable for use as an internal standard in various analytical techniques.
Uses
Used in Pharmaceutical Industry:
ACETAMINOPHEN-D3 is used as an internal standard for the quantification of Paracetamol (Acetaminophen) by Gas Chromatography (GC) or Liquid Chromatography (LC) mass spectrometry. This application is crucial in ensuring accurate and reliable measurements of Paracetamol levels in pharmaceutical formulations, clinical samples, and other related research.
Used in Medical Applications:
Labelled Acetaminophen (A161220) is utilized as an analgesic and antipyretic agent. It helps in relieving pain and reducing fever, making it a valuable component in the treatment of various medical conditions that involve discomfort and elevated body temperature.
Used in Research and Development:
Due to its stable isotopic composition, ACETAMINOPHEN-D3 is also employed in research and development for the synthesis and characterization of new pharmaceutical compounds, as well as in the study of drug metabolism and pharmacokinetics.
Check Digit Verification of cas no
The CAS Registry Mumber 60902-28-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,9,0 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 60902-28:
(7*6)+(6*0)+(5*9)+(4*0)+(3*2)+(2*2)+(1*8)=105
105 % 10 = 5
So 60902-28-5 is a valid CAS Registry Number.
60902-28-5Relevant articles and documents
High Resolution NMR Spectroscopic Studies on the Metabolism and Futile Deacetylation of 4-Hydroxyacetanilide (Paracetamol) in the Rat
Nicholls, Andrew W.,Caddick, Stephen,Wilson, Ian D.,Farrant, R. Duncan,Lindos, John C.,Nicholson, Jeremy K.
, p. 1155 - 1164 (1995)
Paracetamol (4-hydroxyacetanilide, acetaminophen) was synthesized with the acetyl group labelled with C2H3 (paracetamol-C2H3), and dosed to rats i.p. at 25 mg/kg (N = 5) and 40 mg/kg (N = 3) body weight. Paracet
Preparation of labeled human drugmetabolites and drug-drug interaction-probes with fungal peroxygenases
Poraj-Kobielska, Marzena,Atzrodt, Jens,Holla, Wolfgang,Sandvoss, Martin,Groebe, Glenn,Scheibner, Katrin,Hofrichter, Martin
, p. 513 - 519 (2014/03/21)
Enzymatic conversion of a drug can be an efficient alternative for the preparation of a complex metabolite compared with a multi-step chemical synthesis approach. Limitations exist for chemical methods for direct oxygen incorporation into organic molecule
