60979-14-8

Basic information

• Product Name: Benzene, 1-nitro-4-(pentafluoroethyl)-
• Synonyms: p-(pentafluoroethyl)nitrobenzene;1-nitro-4-(1,1,2,2,2-pentafluoroethyl)-benzene;1-Pentafluoroethyl-4-nitrobenzene;1-nitro-4-(pentafluoroethyl)benzene;1-Nitro-4-(perfluoroethyl)benzene;4-Pentafluoroethyl-nitrobenzene;Benzene,1-nitro-4-(pentafluoroethyl)
• CAS NO: 60979-14-8
• Molecular Formula: C8H4F5NO2
• Molecular Weight: 241.117
• Mol File: 60979-14-8.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: Benzene, 1-nitro-4-(pentafluoroethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-nitro-4-(pentafluoroethyl)-(60979-14-8)
• EPA Substance Registry System: Benzene, 1-nitro-4-(pentafluoroethyl)-(60979-14-8)

Safety Data

• Hazardous Substances Data: 60979-14-8(Hazardous Substances Data)

Upstream product

• 636-98-6 p-nitrobenzene iodide 
• 3834-42-2 (heptafluoropropyl)trimethylsilane 
• 124898-13-1 trimethyl(pentafluoroethyl)silane 
• 378-77-8 sodium pentafluoropropionate 
• 120120-26-5 (trifluoromethyl)triethylsilane 
• 378-76-7 Potassium pentafluoropropionate 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 75-05-8 acetonitrile 
• 100-01-6 4-nitro-aniline 
• 60007-39-8 pentafluoroethylcopper(I) 
• 116-14-3 polytetrafluoroethylene 
• 24067-17-2 4-nitrophenylboronic acid 
• 586-78-7 para-nitrophenyl bromide 
• 58808-61-0 α,α,α-trifluoro-4-nitroacetophenone 

Downstream Products

• 60979-04-6 4-(1,1,2,2,2-pentafluoroethyl)-phenylamine 

Relevant articles and documents

Copper-mediated pentafluoroethylation of organoboronates and terminal alkynes with TMSCF3

The TMSCF3-derived CuCF2CF3 species has been successfully applied in pentafluoroethylation of organoboronates and terminal alkynes. By using 1,10-phenanthroline as a ligand, a broad range of (hetero)arylboronates and alkenylboronates were smoothly pentafluoroethylated under aerobic conditions. Furthermore, terminal alkynes can undergo aerobic cross-coupling with the TMSCF3-derived CuCF2CF3 species in the absence of additional ligands.

NOVEL METHOD FOR PRODUCING PERFLUOROALKYLATING AGENTS USING MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL, AND METHOD FOR PRODUCING AROMATIC PERFLUOROALKYL COMPOUNDS USING THE SAME

To provide a simple method for producing silylated trifluoromethylcarbinol from trifluoromethane.SOLUTION: There is provided a method for producing a compound represented by the formula [1], in which the compound is obtained by reacting a monohydroperfluoroalkane, a carbonyl compound, and NaH in an organic solvent and then reacting the reaction solution with a silylating agent. [In the formula, RF is an alkyl group such as a linear chain of C1 to 2, and a perfluoroalkyl group in which all H on C is substituted with F; R1 and R2 are independently alkyl groups such as a linear chain of H or C1 to 2, or the like respectively; R1 and R2 may be integrated to form a ring; and R3, R4 and R5 are independently H or C1 to 2 linear alkyl groups, or the like respectively.]SELECTED DRAWING: None

NOVEL METHOD FOR PRODUCING PERFLUOROALKYLATING AGENTS USING MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL, AND METHOD FOR PRODUCING AROMATIC PERFLUOROALKYL COMPOUND USING THE SAME

PROBLEM TO BE SOLVED: To provide a method for producing an aromatic perfluoroalkyl compound using silylated trifluoromethyl carbinol. SOLUTION: There is provided a method for producing an aromatic perfluoroalkyl compound represented by the general formula [10], in which a compound represented by the formula [9] and a compound represented by the formula [1] are reacted in an organic solvent in the presence of a copper catalyst, a nitrogen ligand and a metal fluoride. R7-X...[9], RF-R7...[10] [In the formula, R7 is an aryl group or the like which may have a substituent; X is F, Cl, Br or I; RF is an alkyl group such as a linear chain of C1-2, and a perfluoroalkyl group in which all H on C is substituted with F; R1 and R2 are each independently H or a C1-2 linear alkyl group, or the like; R1 and R2 may be integrated to form a ring; and R3, R4 and R5 are each independently H or a C1-2 linear alkyl group, or the like.] SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT