6098-44-8 Usage
Description
Acetoxyacetylaminofluorene, also known as 2-acetamidofluorene with an acetoxy group substitution on nitrogen, is a chemical compound derived from 2-acetamidofluorene. It is characterized by its unique molecular structure, which includes an acetoxy group attached to the nitrogen atom of the parent compound.
Uses
Used in Chemical Research:
Acetoxyacetylaminofluorene is used as a research compound for studying the properties and reactions of acetoxy-substituted 2-acetamidofluorene derivatives. Its unique structure allows scientists to explore various chemical reactions and interactions, potentially leading to the development of new compounds with specific applications.
Used in Pharmaceutical Development:
Due to its structural similarities with other bioactive compounds, Acetoxyacetylaminofluorene may be used as a starting material or intermediate in the synthesis of pharmaceuticals. Its potential applications in drug development could include the creation of new therapeutic agents for various medical conditions.
Used in Material Science:
The unique properties of Acetoxyacetylaminofluorene may also make it a valuable component in the development of new materials for various industries. Its potential applications could range from the creation of advanced polymers to the development of novel coatings or adhesives with specific properties.
Safety Profile
Questionable carcinogen withexperimental tumorigenic and neoplastigenic data. Humanmutation data reported. When heated to decomposition itemits toxic fumes of NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 6098-44-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,9 and 8 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6098-44:
(6*6)+(5*0)+(4*9)+(3*8)+(2*4)+(1*4)=108
108 % 10 = 8
So 6098-44-8 is a valid CAS Registry Number.
InChI:InChI=1/C17H15NO3/c1-11(19)18(21-12(2)20)15-7-8-17-14(10-15)9-13-5-3-4-6-16(13)17/h3-8,10H,9H2,1-2H3
6098-44-8Relevant articles and documents
Thissen,Duncan
, p. 59,60,61 (1978)
Substituent effects on the bioactivation of 2-(N-hydroxyacetamido)fluorenes by N-arylhydroxamic acid N,O-cyltransferase
Elfarra,Hanna
, p. 1453 - 1460 (2007/10/02)
A series of 7-substituted analogues of 2-(N-hydroxyacetamido)fluorene (1) was subjected to bioactivation by a partially purified preparation of hamster hepatic AHAT, and the rates of methylthio adduct formation resulting from the reaction of the activated intermediates with N-acetylmethionine were determined. Electronegative substituents enhanced the amount of adduct formed; this finding contrasted with the results of a previous study in which it was found that electron-donating substituents facilitated the mechanism-based inactivation of AHAT by analogues of 1. The structures of the adducts formed from reaction of the activated forms of several of the 7-substituted compounds with N-acetylmethionine and with 2'-deoxyguanosine were determined; the types of adducts formed were similar to those formed with electrophiles generated by the AHAT-catalyzed activation of 1. Electronegative substituents enhanced the amount of adducts formed in the reaction with 2'-deoxyguanosine as well as with N-acetylmethionine.
Reactivities of the carcinogens, N-hydroxy-2-fluorenylacetamide and N-hydroxy-3-fluorenylacetamide, with tissue nucleophiles.
Zieve,Gutmann
, p. 471 - 476 (2007/10/14)
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