610800-52-7

Basic information

• Product Name: N-methyl-N-nosyl-L-leucine methyl ester
• CAS NO: 610800-52-7
• Molecular Weight: 344.389
• Mol File: 610800-52-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-methyl-N-nosyl-L-leucine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-nosyl-L-leucine methyl ester(610800-52-7)
• EPA Substance Registry System: N-methyl-N-nosyl-L-leucine methyl ester(610800-52-7)

Safety Data

• Hazardous Substances Data: 610800-52-7(Hazardous Substances Data)

Upstream product

• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 186581-53-3 diazomethane 
• 203873-66-9 (S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate 

Relevant articles and documents

"One-pot" methylation of N-nosyl-α-amino acid methyl esters with diazomethane and their coupling to prepare N-methyl dipeptides

N-Nosyl-α-amino acid methyl esters are methylated quantitatively with diazomethane. After proper deprotection of the amino function by treatment with the reagent system mercaptoacetic acid/sodium methoxide, the obtained N-methyl amino acid methyl esters are coupled with N-Fmoe amino acid chlorides to afford the corresponding dipeptides. The obtained products do not show any detectable extent of racemization by 1H NMR and HPLC.