203873-66-9

Basic information

• Product Name: (S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate
• Synonyms: (S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate
• CAS NO: 203873-66-9
• Molecular Weight: 330.362
• Mol File: 203873-66-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate(203873-66-9)
• EPA Substance Registry System: (S)-methyl 4-methyl-2-(4-nitrophenylsulfonamido)pentanoate(203873-66-9)

Safety Data

• Hazardous Substances Data: 203873-66-9(Hazardous Substances Data)

Upstream product

• 2666-93-5 (S)-Leu-OMe 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 7517-19-3 methyl (L)-leucinate hydrochloride 

Downstream Products

• 203873-69-2 (S)-methyl 2-(N-allyl-4-nitrophenylsulfonamido)-4-methylpentanoate 
• 610800-52-7 N-methyl-N-nosyl-L-leucine methyl ester 
• 916049-31-5 4-methyl-2-[(4-nitrobenzenesulfonyl)trimethylsilanylmethylamino]pentanoic acid methyl ester 
• 916049-49-5 2-[(3-benzyloxycarbonylaminopropionyl)methoxymethylamino]-4-methylpentanoic acid methyl ester 
• 916049-34-8 2-[(3-benzyloxycarbonylaminopropionyl)trimethylsilylmethylamino]-4-methylpentanoic acid methyl ester 
• 2666-93-5 (S)-Leu-OMe 
• 1243654-89-8 N-ethyl-N-nosyl-L-leucine methyl ester 
• 1492-11-1 N-acetyl-L-leucine methyl ester 

Relevant articles and documents

Chemoselective Intramolecular Functionalization of Methyl Groups in Nonconstrained Molecules Promoted by N-Iodosulfonamides

Mechanistic evidence observed in Hofmann-L?ffler-Freytag-type reactions has been crucial to achieve the chemoselective functionalization of methyl groups under mild conditions. Radical-mediated methyl iodination and subsequent oxidative deiodination are the key steps in this functionalization, where iodine chemistry has a pivotal role on the formation of the C-N bond. The concepts of single hydrogen atom transfer (SHAT) and multiple hydrogen atom transfer (MHAT) are introduced to describe the observed chemoselectivity. (Chemical Equation Presented).

Synthesis of Optically Active 2,3-Disubstituted Indoline -Derivatives through Cycloaddition Reactions between Benzynes and α,β-Unsaturated γ-Aminobutyronitriles

We report a method for synthesizing optically active 2,3-disubstituted indolines by the cycloaddition reaction of benzynes with various 4-[(4-toluenesulfonyl)amino]-(E)-but-2-enenitriles, which are readily prepared from the corresponding l -amino acid der

Building functionalized peptidomimetics: Use of electroauxiliaries for introducing N-acyliminium ions into peptides

A series of silyl-substituted amino acids have been synthesized, inserted into peptides, and then employed as precursors for oxidatively generating reactive N-acyliminium ions. Both electrochemical and chemical oxidation procedures have been employed. N-Acyliminium ion generation in a solid-phase substrate as well as application to a small library of functionalized dipeptides has been demonstrated. Limitations in terms of how electron-rich the silyl groups can be as well as the compatibility of multiple silyl groups within a longer peptide are defined.