61319-45-7Relevant articles and documents
27. Carotinoid-Glycosylester. Synthese von 8'-Apo-β-carotin-8'-saure-(β-D-glucosyl)ester und Vitamin-A-saure-(β-D-glucosyl)ester
Pfander, Hanspeter,Laderach, Manfred,Wittwer, Fritz
, p. 277 - 283 (1980)
β-D-glucosyl 8'-apo-β-carotene-8'-oate (III) and β-D-glucosyl vitamin-A-oate (VI) were regio- and stereoselctively synthesized in high yields from the N-acyl-imidazoles I and IV, respectively, or from the N-acyltriazoles II and V, resprctively, and unprotected β-D-glucose, according to the method described for the synthesis of di(β-D-glucosyl) 8,8'-diapo-carotene8,8'-dioate .It seems that this method can generally be applied for the synthesis of β-D-glucosyl esters of polyene carboxylic acids.
Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice
Patel, Jyoti B.,Huynh, Carlic K.,Handratta, Venkatesh D.,Gediya, Lalji K.,Brodie, Angela M. H.,Goloubeva, Olga G.,Clement, Omoshile O.,Nanne, Ivo P.,Soprano, Dianne Robert,Njar, Vincent C. O.
, p. 6716 - 6729 (2007/10/03)
Novel retinoic acid metabolism blocking agents (RAMBAs) have been synthesized and characterized. The synthetic features include introduction of nucleophilic ligands at C-4 of all-trans-retinoic acid (ATRA) and 13-cis-retinoic acid, and modification of ter