61367-11-1 Usage
Description
(4-[(2-chloroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl formate is a complex chemical compound characterized by its unique structure, which includes a cyclohexyl ring, an amino group, a carbamoyl and nitroso group attached to the amino group, a 2-chloroethyl group, and a formate group. The presence of these functional groups indicates its potential for diverse applications across various industries.
Uses
Used in Pharmaceutical Industry:
(4-[(2-chloroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl formate is used as a potential pharmaceutical compound for its unique structure and functional groups, which may offer novel therapeutic properties and applications in drug development.
Used in Agricultural Industry:
In the agricultural sector, (4-[(2-chloroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl formate could be utilized as a chemical intermediate or active ingredient in the development of new pesticides, herbicides, or other agrochemicals, thanks to its complex structure and functional groups.
Used in Materials Science:
(4-[(2-chloroethyl)(nitroso)carbamoyl]aminocyclohexyl)methyl formate may also find applications in materials science, where its unique structure and functional groups could be exploited to create new materials with specific properties, such as improved strength, durability, or chemical resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 61367-11-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,6 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 61367-11:
(7*6)+(6*1)+(5*3)+(4*6)+(3*7)+(2*1)+(1*1)=111
111 % 10 = 1
So 61367-11-1 is a valid CAS Registry Number.
61367-11-1Relevant articles and documents
Synthesis of analogues of N (2 chloroethyl) N' trans 4 methylcyclohexyl) N nitrosourea for evaluation as anticancer agents
Johnston,McCaleb,Clayton,Frye,Krauth,Montgomery
, p. 279 - 290 (2007/10/04)
The superior activity of N (2 chloroethyl) N' (trans 4 methylcyclohexyl) N nitrosourea (MeCCNU) against advanced murine Lewis lung carcinoma in comparisons with the cis form and other nitrosoureas prompted the synthesis of a number of MeCCNU analogues, including several cis trans pairs. The methyl group was replaced by a variety of substituents (CO2H, CH2CO2H, CO2Me, CH2OAc, CH2Cl, OMe); the trans 3 methylcyclohexyl, cis 2 methyl 1,3 dithian 5 yl, cis and trans 2 methyl 1,3 dithian 5 yl tetraoxide, and 1 methylhexyl (open chain) analogues were also prepared. Preliminary tests against murine leukemia L1210 revealed therapeutic indices (ED50/LD10) ranging from 0.26 to 0.79; all but 3 analogues effected 50% cure rates at nontoxic doses, the open chain analogue being one of the least active. In terms of therapeutic index, diequatorial (trans 4) isomers were, with one exception, as active as or, in 4 of the 8 examples, somewhat more active than the corresponding axial equatorial (cis 4) isomers. In this series, 4 of the 5 2-fluoroethyl analogues prepared were clearly inferior to the corresponding 2 chloroethyl analogues.
