61668-02-8

Basic information

• Product Name: 3-Buten-1-one, 1-(4-fluorophenyl)-
• Synonyms: p-Fluorophenyl propenyl ketone
• CAS NO: 61668-02-8
• Molecular Formula: C10H9FO
• Molecular Weight: 164.179
• Mol File: 61668-02-8.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: 3-Buten-1-one, 1-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Buten-1-one, 1-(4-fluorophenyl)-(61668-02-8)
• EPA Substance Registry System: 3-Buten-1-one, 1-(4-fluorophenyl)-(61668-02-8)

Safety Data

• Hazardous Substances Data: 61668-02-8(Hazardous Substances Data)

Upstream product

• 52-86-8 haloperidol 
• 403-43-0 4-fluorobenzoyl chloride 
• 762-72-1 allyl-trimethyl-silane 
• 459-57-4 4-fluorobenzaldehyde 
• 86718-78-7 1-(4-fluorophenyl)-3-buten-1-ol 

Downstream Products

• 1453859-73-8 (Z)-1-(4-fluorophenyl)but-2-en-1-one 
• 28122-15-8 (E)-1-(4-fluorophenyl)but-2-en-1-one 
• 472976-39-9 C₁₀H₉FN₄O 
• 1612790-49-4 (4-fluorophenyl)(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)methanone 
• 491875-99-1 3-(4-fluoro-phenyl)-5-methylisoxazole 
• 1616603-22-5 C₁₂H₁₂FNO₂ 
• 110319-94-3 2-(4-fluorophenyl)-1H-pyrrole 
• 1017260-90-0 (S)-1-(4’-fluorophenyl)butan-1,4-diol 
• 1420031-28-2 (S)-5-benzyl-3-(4-fluorophenyl)-4,5-dihydroisoxazole 
• 833462-37-6 3-(4-fluorophenyl)-5-[(phenylselanyl)methyl]-4,5-dihydroisoxazole 

Relevant articles and documents

Visible Light-Promoted Recyclable Carbon Nitride-Catalyzed Dioxygenation of β,γ-Unsaturated Oximes

A visible-light-induced dioxygenation of β,γ-unsaturated oximes for the synthesis of diverse useful isoxazolines bearing a hydroxyl moiety was developed by employing graphitic carbon nitride (g-C3N4) as a heterogeneous photocatalyst under an air atmosphere. Noted that, the eminent advantages of this metal-free protocol include step economy, easy operation, a recyclable photocatalyst, external reductant-/oxidant-free and mild reaction conditions. Additionally, mechanistic studies indicated hydroxyl radical was generated under the photocatalysis of g-C3N4.

Copper-catalyzed radical oxyallylation of olefins for the construction of alkene-containing isoxazolines

A radical-mediated approach to alkene oxyallylation using allylic oximes is described. The reaction proceeds under copper-catalytic redox-neutral conditions and tolerates various functional groups. This protocol thus enables the synthesis of structurally valuable isoxazolines and the introduction of a versatile olefin motif in a single step.

Photoinduced Olefin Diamination with Alkylamines

Vicinal diamines are ubiquitous materials in organic and medicinal chemistry. The direct coupling of olefins and amines would be an ideal approach to construct these motifs. However, alkene diamination remains a long-standing challenge in organic synthesis, especially when using two different amine components. We report a general strategy for the direct and selective assembly of vicinal 1,2-diamines using readily available olefin and amine building blocks. This mild and straightforward approach involves in situ formation and photoinduced activation of N-chloroamines to give aminium radicals that enable efficient alkene aminochlorination. Owing to the ambiphilic nature of the β-chloroamines produced, conversion into tetra-alkyl aziridinium ions was possible, thus enabling diamination by regioselective ring-opening with primary or secondary amines. This strategy streamlines the preparation of vicinal diamines from multistep sequences to a single chemical transformation.