618902-05-9

Basic information

• Product Name: 3-[5-bromo-3-(2,6-difluoro-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester
• Synonyms: 3-[5-bromo-3-(2,6-difluoro-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 618902-05-9
• Molecular Weight: 500.34
• Mol File: 618902-05-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[5-bromo-3-(2,6-difluoro-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[5-bromo-3-(2,6-difluoro-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester(618902-05-9)
• EPA Substance Registry System: 3-[5-bromo-3-(2,6-difluoro-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester(618902-05-9)

Safety Data

• Hazardous Substances Data: 618902-05-9(Hazardous Substances Data)

Upstream product

• 103057-44-9 N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine 
• 352303-66-3 5-bromo-1-(2,6-difluoro-benzyl)-6-methyl-1H-pyrimidine-2,4-dione 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 352298-02-3 1-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-6-methyl-3-pyrrolidin-3-yl-1H-pyrimidine-2,4-dione 
• 618902-06-0 3-[3-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis and structure-activity relationships of 1-arylmethyl-3-(1-methyl-2-amino)ethyl-5-aryl-6-methyluracils as antagonists of the human GnRH receptor

A new class of small molecule GnRH antagonists, the 1-arylmethyl-3-(1-methyl-2-amino)ethyl-5-aryl-6-methyluracils, was designed and a novel stereoselective synthesis for these compounds was developed. The stereochemical integrities of key intermediates (S