61898-56-4Relevant articles and documents
Consturuction of a complete bioelectrocatalytic electrode composed of alcohol dehydrogenase-and all electron-transfer components-modified graphite felt for diol oxidation
Kashiwagi, Yoshitomo,Pan, Qinghai,Kurashima, Futoshi,Kikuchi, Chikara,Anzai, Jun-ichi,Osa, Tetsuo
, p. 143 - 144 (1998)
A poly(acrylic acid)-coated graphite felt electrode immobilizing all bioelectrochemical reaction components of ferrocene, diaphorase, NADH and alcohol dehydrogenase in the domain of the poly(acrylic acid) layer was applied to oxidize electrocatalytically cis-1,2-cyclohexanedimethanol and 3-methyl-1,5-pentanediol to (+)-(1R,6S)-cis-8-oxabicyclo[4.3.0]nonan-7-one and (3S)-3-methyl-δ-valerolactone, respectively, in a 0.15 M phosphate buffer (pH 8.0) at the constant potential of 0.45 V vs. SCE with high current efficiency (>92%) and high optical purity (>92%).
Photobiocatalytic alcohol oxidation using LED light sources
Rauch,Schmidt,Arends,Oppelt,Kara,Hollmann
supporting information, p. 376 - 379 (2017/08/14)
The photocatalytic oxidation of NADH using a flavin photocatalyst and a simple blue LED light source is reported. This in situ NAD+ regeneration system can be used to promote biocatalytic, enantioselective oxidation reactions. Compared to the traditional use of white light bulbs this method enables very significant reductions in energy consumption and CO2 emission.
Desymmetrization of acid anhydride with asymmetric esterification catalyzed by chiral phosphoric acid
Yamada, Ken-ichi,Oonishi, Akinori,Kuroda, Yusuke,Harada, Shingo,Kiyama, Hiroki,Yamaoka, Yousuke,Takasu, Kiyosei
supporting information, p. 4098 - 4100 (2016/08/18)
Asymmetric desymmetrization of σ-symmetric acid anhydrides was achieved with chiral phosphoric acid as a Br?nsted acid catalyst. The key of success was finding of benzhydrol and 2,2-diphenylethanol as the nucleophiles of choice. The corresponding half esters were obtained in good yields with high selectivity.
A new method for the preparation of non-terminal alkynes: Application to the total syntheses of tulearin A and C
Lehr, Konrad,Schulthoff, Saskia,Ueda, Yoshihiro,Mariz, Ronaldo,Leseurre, Lucie,Gabor, Barbara,Fürstner, Alois
, p. 219 - 227 (2015/02/19)
Lactones are known to react with the reagent generated in situ from CCl4 and PPh3 in a Wittig-type fashion to give gem-dichloro-olefin derivatives. Such compounds are now shown to undergo reductive alkylation on treatment with organolithium reagents RLi to furnish acetylene derivatives bearing the substituent R at their termini (R=Me, n-, sec-, tert-alkyl, silyl); the reaction can be catalyzed with either Cu(acac)2 or Fe(acac)3/1,2-diaminobenzene. Two alkynol derivatives prepared in this way from readily accessible lactone precursors served as the key building blocks for the total syntheses of the cytotoxic marine macrolides tulearin A (1) and C (2). The assembly of these fragile targets hinged upon ring closing alkyne metathesis (RCAM) followed by a formal trans-reduction of the resulting cycloalkynes via trans-hydrosilylation/protodesilylation.
