62051-68-7Relevant articles and documents
meso- and rac-2,7-Diphenyl-3,5-octadiyne-2,7-diol, C20H18O2
Lord, M. D.,Winter, R. E. K.,Rath, N. P.
, p. 116 - 120 (1994)
The stereoisomeric forms of 2,7-diphenyl-3,5-octadiyne-2,7-diol (I) have been identified; meso- and rac-(I) exhibit different crystal packing, reflecting very different hydrogen-bonding networks.
Copper powder-mediated homocoupling reactions of iodoacetylenes to synthesize symmetrical 1,3-butadiynes
Xue, Song,Meng, Ling-Guo,Guo, Qing-Xiang
, p. 2243 - 2251 (2008/09/21)
A new route to synthesize symmetrical 1,3-butadiynes from iodoacetylenes in the presence of copper powder and pyridine was developed. Moderate to excellent yields were obtained through an efficient and simple process involving the copper powder without any further activation. Copyright Taylor & Francis Group, LLC.
PMHS-mediated couplings of alkynes or benzothiazoles with various electrophiles: Application to the synthesis of (-)-akolactone A
Gallagher, William P.,Maleczka Jr., Robert E.
, p. 6775 - 6779 (2007/10/03)
Polymethylhydrosiloxane (PMHS) in combination with CsF facilitates the cross-coupling of alkynes or benzothiazoles with an array of vinyl, styryl, and aryl halides or nonaflates as well as acid chlorides. Experimental and spectroscopic evidence indicates that these reactions involve the in situ generation of a siloxyl intermediate. These cross-couplings proceed relatively quickly at room temperature and under amine-free conditions. To demonstrate the applicability of the method, a total synthesis of the cyctotoxic butanolide (-)-akolactone A was carried out.
