62234-36-0 Usage
Description
N-α-Z-N-β-Boc-D-2,3-diaminopropionic acid, also known as N-alpha-Benzyloxycarbonyl-3-(Boc-amino)-D-alanine, is a white crystalline powder with unique chemical properties. It is a derivative of D-2,3-diaminopropionic acid, featuring a benzyloxycarbonyl (Z) group at the α-amino position and a tert-butyloxycarbonyl (Boc) group at the β-amino position. These protective groups are commonly used in organic synthesis to protect the amino groups from unwanted reactions.
Uses
Used in Pharmaceutical Industry:
N-α-Z-N-β-Boc-D-2,3-diaminopropionic acid is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of novel drugs with potential applications in treating different medical conditions.
Used in Peptide Synthesis:
In the field of peptide chemistry, N-α-Z-N-β-Boc-D-2,3-diaminopropionic acid serves as a building block for the construction of complex peptide sequences. The protective Boc and Z groups facilitate the stepwise assembly of peptides, preventing unwanted side reactions and ensuring the desired product is obtained.
Used in Research and Development:
N-α-Z-N-β-Boc-D-2,3-diaminopropionic acid is also utilized in research and development for studying the structure-activity relationships of various bioactive peptides and proteins. Its unique structure allows scientists to probe the effects of specific modifications on the biological activity of these molecules.
Used in Chemical Synthesis:
N-α-Z-N-β-Boc-D-2,3-diaminopropionic acid can be employed as a starting material or a synthetic intermediate in the preparation of other organic compounds, such as chiral catalysts, ligands, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 62234-36-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,2,3 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 62234-36:
(7*6)+(6*2)+(5*2)+(4*3)+(3*4)+(2*3)+(1*6)=100
100 % 10 = 0
So 62234-36-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H22N2O6/c1-16(2,3)24-15(22)18-12(13(19)20)9-17-14(21)23-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,18,22)(H,19,20)
62234-36-0Relevant articles and documents
PRODRUGS OF MODULATORS OF THE NMDA RECEPTOR
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Page/Page column 50-51, (2021/01/23)
The present invention is directed to novel prodrugs of modulators of the NMDA receptor of formula I. Separate aspects of the inventions are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat neurological disorders or neuropsychiatric disorders such as depression.
PYRROLOBENZODIAZEPINE DIMER PRECURSOR AND LIGAND-LINKER CONJUGATE COMPOUND THEREOF
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, (2020/02/18)
The present invention relates to a pyrrolobenzodiazepine dimer prodrug and a ligand-linker conjugate compound thereof, a composition containing these, and therapeutic use thereof particularly as an anticancer drug. The stability of the compounds themselves and the stability thereof in plasma are excellent and the compounds are advantageous in terms of manifestation of toxicity, and thus the compounds are industrially useful in that it is possible to target proliferative diseases such as cancer, to perform a specific treatment, to maximize the drug efficacy, and to minimize the occurrence of side effects.
Sulfate Encapsulation in Supramolecular Structures from L -Asparagine-Derived 2,5-Diketopiperazine Scaffolds: Anion Binding
Naini, Santhosh Reddy,Lalancette, Roger A.,Gorlova, Olga,Ramakrishna, Kallaganti V. S.,Yadav, Jhillu Singh,Ranganathan, Subramania
, p. 7015 - 7022 (2016/02/19)
We report a new sulfate receptor, anchored onto 2,5-diketopiperazine units, which results in the formation of two types of supramolecules; one in which the sulfate ion guest fits snugly into extended cavities and the other in which the guest is sandwiched between layers. In each case, the anion is held by six hydrogen bonds from the host. 1H NMR spectroscopic solution studies enabled the construction of Job plots, and calculation of stoichiometry and association constants. These findings are of possible significance in drug design and for construction of combinatorial libraries.