623157-95-9

Basic information

• Product Name: N-((1R,2S)-2-hydroxy-1-methyl-2-phenylethyl)-N-methyl-acrylamide
• Synonyms: N-((1R,2S)-2-hydroxy-1-methyl-2-phenylethyl)-N-methyl-acrylamide
• CAS NO: 623157-95-9
• Molecular Weight: 219.283
• Mol File: 623157-95-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-((1R,2S)-2-hydroxy-1-methyl-2-phenylethyl)-N-methyl-acrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((1R,2S)-2-hydroxy-1-methyl-2-phenylethyl)-N-methyl-acrylamide(623157-95-9)
• EPA Substance Registry System: N-((1R,2S)-2-hydroxy-1-methyl-2-phenylethyl)-N-methyl-acrylamide(623157-95-9)

Safety Data

• Hazardous Substances Data: 623157-95-9(Hazardous Substances Data)

Upstream product

• 24221-86-1 (+)-(1S,2R)-ephedrine hydrochloride 
• 814-68-6 acryloyl chloride 

Downstream Products

• 623158-09-8 (2R,4R,5S)-4-[((1R,2S)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-methyl-carbamoyl]-5-phenyl-pyrrolidine-2-carboxylic acid ethyl ester 

Relevant articles and documents

Silver acetate-catalysed asymmetric 1,3-dipolar cycloadditions of imines and chiral acrylamides

N-Metallated azomethine ylides were generated by the reaction of arylidene glycine imines with AgOAc and triethylamine. These azomethine ylides undergo cycloaddition to chiral acrylamides with excellent diastereoselectivity. The configuration of two of the cycloadducts was confirmed by X-ray crystallography.