6261-31-0

Basic information

• Product Name: 1-Naphthalenol, 1,2,3,4-tetrahydro-2-(phenylmethylene)-
• CAS NO: 6261-31-0
• Molecular Formula: C17H16O
• Molecular Weight: 236.313
• Mol File: 6261-31-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-Naphthalenol, 1,2,3,4-tetrahydro-2-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenol, 1,2,3,4-tetrahydro-2-(phenylmethylene)-(6261-31-0)
• EPA Substance Registry System: 1-Naphthalenol, 1,2,3,4-tetrahydro-2-(phenylmethylene)-(6261-31-0)

Safety Data

• Hazardous Substances Data: 6261-31-0(Hazardous Substances Data)

Usage

Physical state

White solid

Solubility

Soluble in organic solvents

Odor

Strong

Uses

Production of dyes, reagent in organic synthesis, chemical intermediate, manufacturing of antioxidants, lubricating oils, and pharmaceuticals

Properties

Antimicrobial and antioxidant

Handling precautions

Toxic and can cause skin and respiratory irritation

Upstream product

• 100-52-7 benzaldehyde 
• 6261-32-1 2-benzylidene-1-tetralone 
• 6261-32-1 (E)-2-benzylidene-1-tetralone 

Downstream Products

• 6261-32-1 (E)-2-benzylidene-1-tetralone 
• 613-59-2 2-benzylnaphthalene 
• 59082-36-9 2-(Benzylidene)-3,4-dihydronaphthalen-1(2H)-on 
• 84787-49-5 1,2-dihydro-9H-benzofluorene 
• 6261-33-2 cis-2-benzyl-1,2,3,4-tetrahydronaphthalene-1-ol 
• 77786-87-9 N-methyl carbamate de benzylidene-2 tetralol 
• 6261-33-2 (1S,2R)-2-benzyl-1,2,3,4-tetrahydronaphthalen-1-ol 
• 6261-33-2 (1R,2S)-2-benzyl-1,2,3,4-tetrahydronaphthalen-1-ol 

Relevant articles and documents

Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol

One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.

Synthesis of polysubstituted quinolines via transition-metal-free oxidative cycloisomerization of o -cinnamylanilines

An efficient synthesis of 2-aryl 4-substituted quinolines from stable and readily available o-cinnamylanilines, prepared from anilines and cinnamylalcohols, has been developed. The reaction occurred via a regioselective 6-endo-trig intramolecular oxidative cyclization using KOtBu as a mediator and DMSO as an oxidant at rt. The reaction showed a broad substrate scope with good to excellent yields.

Anticholinesterase compounds. Structure-activity relationships of carbamates and phosphates

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