6265-91-4

Basic information

• Product Name: 2-(4-CHLOROPHENYL)BENZOTHIAZOLE
• Synonyms: 2-(4-CHLOROPHENYL)BENZOTHIAZOLE;2-Cpbt;Benzothiazole, 2-(4-chlorophenyl)-;2-(4-chlorophenyl)benzo[d]thiazole;4-(2-Benzothiazolyl)-1-chlorobenzene
• CAS NO: 6265-91-4
• Molecular Formula: C₁₃H₈ClNS
• Molecular Weight: 245.73
• Mol File: 6265-91-4.mol
• Article Data: 299

Chemical Properties

• Melting Point: 118 °C
• Boiling Point: 381.9 °C at 760 mmHg
• Flash Point: 184.8 °C
• Appearance: /
• Density: 1.339 g/cm³
• Vapor Pressure: 1.08E-05mmHg at 25°C
• Refractive Index: 1.689
• Solubility: soluble in Toluene
• CAS DataBase Reference: 2-(4-CHLOROPHENYL)BENZOTHIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLOROPHENYL)BENZOTHIAZOLE(6265-91-4)
• EPA Substance Registry System: 2-(4-CHLOROPHENYL)BENZOTHIAZOLE(6265-91-4)

Safety Data

• Hazardous Substances Data: 6265-91-4(Hazardous Substances Data)

Usage

General Description

2-(4-chlorophenyl)benzothiazole is a chemical compound with the molecular formula C13H8ClNS. It is a benzothiazole derivative with a 4-chlorophenyl group attached. This chemical is primarily used as a fluorescent brightener in the manufacturing of plastics, fibers, coatings, inks, and detergents. It is also used as a UV-protecting agent in various products. 2-(4-chlorophenyl)benzothiazole has been found to have potential toxic effects, and it is important to handle it with care and follow safety guidelines during its production and use.

InChI:InChI=1/C13H8ClNS/c14-10-7-5-9(6-8-10)13-15-11-3-1-2-4-12(11)16-13/h1-8H

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 137-07-5 2-amino-benzenethiol 
• 67213-28-9 4-chloroselenobenzamide 
• 105-64-6 diisopropyl peroxydicarbonate 
• 142505-38-2 N-(4-chlorophenylmethylene)-2-methylthiobenzenamine 
• 5909-74-0 N-phenyl-C-(4-chlorophenyl)nitrone 
• 142505-33-7 N-(4-chlorophenylmethylene)-2-phenylthiobenzenamine 
• 87707-90-2 2-[(2-Amino-phenylsulfanyl)-(4-chloro-phenyl)-methyl]-malonic acid diethyl ester 
• 623-03-0 4-Cyanochlorobenzene 
• 6827-40-3 diethyl 4-chlorobenzylidenemalonate 
• 39145-33-0 2-cyano-3-(4-chlorophenyl)-prop-2-enethioamide 
• 74903-80-3 (Z)-N-hydroxy-4-chloro-benzenecarboximidoyl chloride 
• 104-88-1 4-chlorobenzaldehyde 
• 23566-17-8 bis(4-chlorobenzyl)disulfide 

Downstream Products

• 21223-41-6 2-(4-chloro-phenyl)-3-methyl-benzothiazolium; iodide 
• 53544-71-1 2-(4-chlorophenyl)-6-nitrobenzothiazole 
• 53544-78-8 2-(4-chloro-phenyl)-benzothiazol-6-ylamine 
• 1062586-22-4 (4-(benzo[d]thiazol-2-yl)-phenyl)boronic acid 
• 134384-31-9 2-(4-trifluoromethylphenyl)benzothiazole 
• 90481-40-6 2-(benzo[d]thiazol-2-yl)-5-chlorophenol 
• 6278-73-5 2-(4-aminophenyl)benzothiazole 
• 6265-92-5 2-(4-methoxy-phenyl)-benzothiazole 
• 883-93-2 2-Phenylbenzothiazole 
• 6265-55-0 2-(4-hydroxyphenyl)benzothiazole 
• 17930-02-8 2-(4'-cyanophenyl)benzothiazole 
• 1007375-81-6 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzo-[d]thiazole 

Relevant articles and documents

Synthesis of 2-Arylbenzothiazoles from Nitrobenzenes, Benzylamines, and Elemental Sulfur via Redox Cyclization

A sustainable advanced synthetic method was developed based on redox cyclization for the synthesis of 2-arylbenzothiazoles in good to excellent yields from readily available nitrobenzenes, benzylamines, and elemental sulfur without the use of transition-metal catalysts. This method is remarkable: nitro group reduction, a benzylamine redox reaction, sulfuration, condensation, and cyclization, all proceed in a single step to generate a heterocycle. It is also highly atom-economical and does not require any external oxidizing or reducing agents.

Graphene oxide-catalyzed synthesis of benzothiazoles with amines and elemental sulfur via oxidative coupling strategy of amines to imines

The graphene oxide-catalyzed coupling and cyclization reactions of primary amines with elemental sulfur was developed to afford various optically property benzothiazoles. This coupling and cyclization strategies proceeded under the oxidant system graphene oxide/O2 and constructed carbon-heteroatom (N, S) bonds with amines and elemental sulfur. Due to benzothiazoles as common chromophores, these products exhibited intriguing fluorescence properties, including outstanding Stokes shifts (up to 161 nm) and quantum yields (up to 74%). Utilizing the products’ unique fluorescence response in different solvents, β-naphthothiazole 4a showed excellent aggregation-induced emission properties in 1,2-dichloroethane, which was 60 times higher than in tetrahydrofuran.

Photocatalyst- And Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2)-S Formation

A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.