627489-15-0

Basic information

• Product Name: acetic acid 4,5-bis-benzyloxy-2-iodo-phenyl ester
• Synonyms: acetic acid 4,5-bis-benzyloxy-2-iodo-phenyl ester
• CAS NO: 627489-15-0
• Molecular Weight: 474.295
• Mol File: 627489-15-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: acetic acid 4,5-bis-benzyloxy-2-iodo-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: acetic acid 4,5-bis-benzyloxy-2-iodo-phenyl ester(627489-15-0)
• EPA Substance Registry System: acetic acid 4,5-bis-benzyloxy-2-iodo-phenyl ester(627489-15-0)

Safety Data

• Hazardous Substances Data: 627489-15-0(Hazardous Substances Data)

Upstream product

• 5447-02-9 3,4-dibenzyloxybenzaldehyde 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 100-39-0 benzyl bromide 
• 27688-86-4 3,4-dibenzyloxyphenol 
• 27688-85-3 3,4-Dibenzyloxyphenyl-acetat 

Downstream Products

• 1196985-61-1 4,4,5,5-tetramethyl-2-(2-acetoxyl-4,5-dibenzyloxyphenyl)-1,3,2-dioxaborolane 
• 344303-15-7 5,6-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenyl)-benzofuran-3-carboxylic acid methyl ester 
• 344303-12-4 4,5-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenylethynyl)-phenol 
• 627489-05-8 2-(2,6-dihydroxy-4-methoxy-phenyl)-5,6-dihydroxy-benzofuran-3-carboxylic acid methyl ester 
• 524-12-9 wedelolactone 
• 627489-61-6 acetic acid 4,5-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenylethynyl)-phenyl ester 

Relevant articles and documents

Total Synthesis of Wedelolactone

The total synthesis of wedelolactone, a naturally occurring direct inhibitor of IKK complex that can suppress LPS-induced caspase-11 expression, using a convergent synthetic approach, is described. The key steps involved in this synthesis include the palladium-catalyzed Sonogashira reaction and the palladium-catalyzed carbonylative annulation reaction. This approach allows access to diversified analogues of wedelolactone.