627489-05-8

Basic information

• Product Name: 2-(2,6-dihydroxy-4-methoxy-phenyl)-5,6-dihydroxy-benzofuran-3-carboxylic acid methyl ester
• Synonyms: 2-(2,6-dihydroxy-4-methoxy-phenyl)-5,6-dihydroxy-benzofuran-3-carboxylic acid methyl ester
• CAS NO: 627489-05-8
• Molecular Weight: 346.293
• Mol File: 627489-05-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2,6-dihydroxy-4-methoxy-phenyl)-5,6-dihydroxy-benzofuran-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,6-dihydroxy-4-methoxy-phenyl)-5,6-dihydroxy-benzofuran-3-carboxylic acid methyl ester(627489-05-8)
• EPA Substance Registry System: 2-(2,6-dihydroxy-4-methoxy-phenyl)-5,6-dihydroxy-benzofuran-3-carboxylic acid methyl ester(627489-05-8)

Safety Data

• Hazardous Substances Data: 627489-05-8(Hazardous Substances Data)

Upstream product

• 627489-61-6 acetic acid 4,5-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenylethynyl)-phenyl ester 
• 344303-12-4 4,5-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenylethynyl)-phenol 
• 627489-15-0 acetic acid 4,5-bis-benzyloxy-2-iodo-phenyl ester 
• 627489-10-5 1,3-Bis-benzyloxy-2-ethynyl-5-methoxy-benzene 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 91360-58-6 2,6-bis(benzyloxy)-4-methoxybenzaldehyde 
• 27688-85-3 3,4-Dibenzyloxyphenyl-acetat 
• 27688-86-4 3,4-dibenzyloxyphenol 
• 5447-02-9 3,4-dibenzyloxybenzaldehyde 
• 344303-15-7 5,6-bis-benzyloxy-2-(2,6-bis-benzyloxy-4-methoxy-phenyl)-benzofuran-3-carboxylic acid methyl ester 

Downstream Products

• 524-12-9 wedelolactone 

Relevant articles and documents

Total Synthesis of Wedelolactone

The total synthesis of wedelolactone, a naturally occurring direct inhibitor of IKK complex that can suppress LPS-induced caspase-11 expression, using a convergent synthetic approach, is described. The key steps involved in this synthesis include the palladium-catalyzed Sonogashira reaction and the palladium-catalyzed carbonylative annulation reaction. This approach allows access to diversified analogues of wedelolactone.