627501-40-0

Basic information

• Product Name: 2-Amino-4-(3-bromo-4-hydroxy-5-methoxyphenyl)-3-cyano-7-methyl-4H-pyrrolo[2,3-h]chromene
• Synonyms: 2-Amino-4-(3-bromo-4-hydroxy-5-methoxyphenyl)-3-cyano-7-methyl-4H-pyrrolo[2,3-h]chromene
• CAS NO: 627501-40-0
• Molecular Weight: 426.269
• Mol File: 627501-40-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Amino-4-(3-bromo-4-hydroxy-5-methoxyphenyl)-3-cyano-7-methyl-4H-pyrrolo[2,3-h]chromene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-4-(3-bromo-4-hydroxy-5-methoxyphenyl)-3-cyano-7-methyl-4H-pyrrolo[2,3-h]chromene(627501-40-0)
• EPA Substance Registry System: 2-Amino-4-(3-bromo-4-hydroxy-5-methoxyphenyl)-3-cyano-7-methyl-4H-pyrrolo[2,3-h]chromene(627501-40-0)

Safety Data

• Hazardous Substances Data: 627501-40-0(Hazardous Substances Data)

Upstream product

• 7556-37-8 4-hydroxy-N-methyl-indole 
• 99972-15-3 2-(3-bromo-4-hydroxy-5-methoxybenzylidene)malononitrile 
• 109-77-3 malononitrile 

Relevant articles and documents

Substituted 4-aryl-4h-pyrrolo[2,3-h]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 4H-chromenes and analogs thereof, represented by the Formula (I): wherein R1, R3-R5, A, D, Y and Z are defined herein. The present invention also relates to the discovery that compounds having Formula (I) are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.