62762-73-6Relevant articles and documents
Preparation of 3,4,5-trisubstituted oxazolones by pd-catalyzed coupling of n -alkynyl tert -butyloxycarbamates with aryl halides and related electrophiles
Lu, Zenghui,Cui, Weijian,Xia, Siyuan,Bai, Yihui,Luo, Fang,Zhu, Gangguo
, p. 9871 - 9877,7 (2012/12/12)
A novel palladium-catalyzed approach for the assembly of 3,4,5-trisubstituted oxazolones has been achieved by the coupling of N-alkynyl tert-butyloxycarbamates with aryl halides and related electrophiles, which involves an oxidative addition followed by oxypalladation/reductive elimination. The reaction provides a convenient access to diversely substituted oxazolones in satisfactory yields and shows good functional group compatibility.