62999-86-4

Basic information

• Product Name: N,N,5,5-tetramethyl-1,3-dioxan-2-amine
• Synonyms: 1,3-dioxan-2-amine, N,N,5,5-tetramethyl-; N,N,5,5-Tetramethyl-1,3-dioxan-2-amine
• CAS NO: 62999-86-4
• Molecular Formula: C₈H₁₇NO₂
• Molecular Weight: 159.2261
• Mol File: 62999-86-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 192.4°C at 760 mmHg
• Flash Point: 56.4°C
• Density: 0.97g/cm³
• Vapor Pressure: 0.491mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: N,N,5,5-tetramethyl-1,3-dioxan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N,5,5-tetramethyl-1,3-dioxan-2-amine(62999-86-4)
• EPA Substance Registry System: N,N,5,5-tetramethyl-1,3-dioxan-2-amine(62999-86-4)

Safety Data

• Hazardous Substances Data: 62999-86-4(Hazardous Substances Data)

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 

Downstream Products

• 5336-72-1 dimethyl(diphenylmethyl)amine 
• 100-52-7 benzaldehyde 
• 776-88-5 5,5-dimethyl-2-phenyl-[1,3]dioxane 
• 768-58-1 2-ethyl-5,5-dimethyl-1,3-dioxane 

Relevant articles and documents

A solution and solid state conformation of 2-diphenylphosphinoyl-1,3-dioxanes. The nature of O-C-P anomeric interactions

Diastereoisomeric 2-diphenylphosphinoyl-1,3-dioxanes 1-4 were synthesized either via the Arbuzov reaction of isopropyl diphenylphosphinite with (1,3-dioxan-2-yl) trimethylammonium iodides or via the transacetalization reaction between 1,3-diols and diphenyl (diethoxymethyl) phosphine oxide. The latter reaction afforded less thermodynamically stable isomers of 3 and 4 in a good yield (44 and 56%, respectively). The magnitude of the anomeric effect in this system determined according to the Franck's equation was found to be 19.7 kJ/mol. Both the NMR and X-ray structural data concerning cis-4,6-dimethyl-1,3-dioxane derivatives 4 suggest that the anomeric effect could stem from several interaction, including the no-δ* C-P negative hyper-conjugation and intramolecular hydrogen bond formation.