630050-32-7

Basic information

• Product Name: 3-bromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide
• Synonyms: 3-bromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide
• CAS NO: 630050-32-7
• Molecular Weight: 354.224
• Mol File: 630050-32-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-bromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide(630050-32-7)
• EPA Substance Registry System: 3-bromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide(630050-32-7)

Safety Data

• Hazardous Substances Data: 630050-32-7(Hazardous Substances Data)

Upstream product

• 92755-81-2 N-bromo-p-toluenesulfonamide 
• 14367-96-5 1-(3-bromophenyl)-2-nitroethanone 
• 941-55-9 4-toluenesulfonyl azide 
• 585-76-2 m-bromobenzoic acid 
• 3132-99-8 m-bromobenzoic aldehyde 
• 21849-40-1 dibromamine-T 
• 41085-71-6 bromamine T 
• 39220-96-7 1-(3-bromophenyl)-2-nitroethanol 
• 127-65-1 chloroamine-T 
• 66920-03-4 S-ethyl 3-bromothiobenzoate 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 1638287-22-5 1-(5-bromo-2-methoxyphenyl)-2-(triphenylphosphanylidene)ethanone 
• 80866-82-6 5-bromo-2-methoxy-benzyl alcohol 
• 2476-35-9 5-bromo-2-methoxybenzoic acid 
• 338385-91-4 2-(5-bromo-2-methoxyphenyl)propan-2-ol 
• 1638291-19-6 5-bromo-2-methoxy-N-methyl-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 1638287-34-9 2,5-dibromo-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 1638287-28-1 5-bromo-2-iodo-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 1638287-10-1 5-bromo-2-methoxy-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 1638287-37-2 5-bromo-2-chloro-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 1369576-98-6 4-bromo-4'-methyl-N-(4-methylbenzenesulfonyl)biphenyl-2-carboxamide 

Relevant articles and documents

Controllable construction of isoquinolinedione and isocoumarin scaffolds: Via RhIII-catalyzed C-H annulation of N -tosylbenzamides with diazo compounds

A highly efficient protocol for the synthesis of isoquinolinediones by RhIII-catalyzed C-H activation/annulation/decarboxylation of N-tosylbenzamides with diazo compounds is reported. The switchable synthesis of isocoumarins was also achieved successfully via C-H activation/annulation with slight modification of the reaction conditions. Importantly, the synthetic utility of this new reaction was further demonstrated in an atom-economical and operationally convenient total synthesis of a TDP2 inhibitor derivative from commercially available starting materials.

Co-Catalyzed Synthesis of N-Sulfonylcarboxamides from Carboxylic Acids and Sulfonyl Azides

A Co-catalyzed effective synthesis of N-sulfonylcarboxamides from the reaction of carboxylic acids and organic azides in the presence of isocyanide has been developed. The protocol has the advantages of short time, low temperature, and being oxidant-free, which provides a new and simple approach for the synthesis of N-sulfonylcarboxamides in good to excellent yields with a broad substrate scope.

Unexpected C-C bond cleavage of α-nitroketone in the presence of TsNBr2: A new pathway for C-N bond formation

A new catalyst-free protocol for C-N bond formation via the cleavage of α-nitroketone has been developed. When α-nitroketones are treated with TsNBr2 in the presence of potassium carbonate, unexpected cleavage of C(O)-CHNO2 bond of α-nitroketone was observed followed by the formation of corresponding amide. Various nitroketones could be converted to corresponding amide using this procedure.