63212-89-5

Basic information

• Product Name: Acetaldehyde, [3-(trifluoromethyl)phenoxy]-
• CAS NO: 63212-89-5
• Molecular Formula: C9H7F3O2
• Molecular Weight: 204.149
• Mol File: 63212-89-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Acetaldehyde, [3-(trifluoromethyl)phenoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetaldehyde, [3-(trifluoromethyl)phenoxy]-(63212-89-5)
• EPA Substance Registry System: Acetaldehyde, [3-(trifluoromethyl)phenoxy]-(63212-89-5)

Safety Data

• Hazardous Substances Data: 63212-89-5(Hazardous Substances Data)

Upstream product

• 2145-31-5 (3-trifluoromethylphenoxy)acetonitrile 
• 1190883-14-7 C₁₁H₁₃F₃O₃ 
• 902261-47-6 3-(3-trifluoromethyl-phenoxy)-propane-1,2-diol 
• 63212-88-4 (3-trifluoromethylphenoxy)acetaldehyde diethyl acetal 
• 98-17-9 3-Trifluoromethylphenol 
• 588-26-1 methyl 2-[3-(trifluoromethyl)phenoxy]acetate 
• 22897-99-0 ethyl (3-trifluoromethylphenoxy)acetate 

Downstream Products

• 88462-65-1 (+/-)-4-[(3-trifluoromethyl)phenoxy]-1-butyne-3-ol 
• 301834-96-8 (3R)-4-[3-(trifluoromethyl)phenoxy]-3-hydroxy-1-butyne 
• 301834-95-7 (R)-4-[3-(trifluoromethyl)phenoxy]-1-butyne-3-yl butyrate 
• 63212-91-9 1-(2-Tetrahydropyranyloxy)-4-acetoxy-5-(3-trifluoromethylphenoxy)pentane 
• 63212-90-8 1-(2-Tetrahydropyranyloxy)-4-acetoxy-5-(3-trifluoromethylphenoxy)-2-pentyne 
• 301834-98-0 (R)-tert-butyldimethyl((1-(3-(trifluoromethyl)phenoxy)but-3-yn-2-yl)oxy)silane 
• 88462-67-3 4-(m-trifluoromethylphenoxy)-3-trimethylsilyloxy-1-butyne 

Relevant articles and documents

Structure-activity relationship studies and sleep-promoting activity of novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 2

Replacement of the dimethoxyphenyl moiety in the core skeleton of almorexant by appropriately substituted imidazoles afforded novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as potent dual orexin receptor antagonists. We describe in th

9,11-cycloendoperoxide pro-drugs of prostaglandin analogues for treatment of ocular hypertension and glaucoma

9,11-Cycloendoperoxide derivatives of biologically active prostaglandin analogs, and particularly of the ocular hypotensive drugs Bimatoprost, Latanaprost, Unoprostone, Travoprost and prostaglandin H2 1-ethanolamide or of structurally closely related analogs, are pro-drugs which hydrolyze under physiological conditions to provide prostaglandin analogues that are capable of providing sustained ocular and other in vivo concentrations of the respective drugs. The compounds of the invention have the formula shown below where the variables have the meaning defined in the specification.

PROSTANOIDS. V. THE ω-CHAIN FOR 16-ARYLOXYTETRANORPROSTAGLANDINS

During hydrostannylation of 4-aryloxy-3-hydroxy-1-butynes and subsequent cleavage of the obtained E-vinylstannates with iodine the corresponding E-1-iodo-3-hydroxy-4-aryloxy-1-butenes were synthesized.