6346-00-5

Basic information

• Product Name: 2-[2-(hydroxymethyl)phenyl]ethanol
• CAS NO: 6346-00-5
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.1904
• Mol File: 6346-00-5.mol
• Article Data: 34

Chemical Properties

• Boiling Point: 296°C at 760 mmHg
• Flash Point: 144.9°C
• Density: 1.139g/cm³
• Vapor Pressure: 0.000665mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 2-[2-(hydroxymethyl)phenyl]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(hydroxymethyl)phenyl]ethanol(6346-00-5)
• EPA Substance Registry System: 2-[2-(hydroxymethyl)phenyl]ethanol(6346-00-5)

Safety Data

• Hazardous Substances Data: 6346-00-5(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Slightly sweet

Solubility

Soluble in water

Specific content

Commonly used as a fragrance ingredient in cosmetic and personal care products
Used in the manufacturing of pharmaceuticals and other industrial products
Utilized as a solvent and a chemical intermediate
Has antimicrobial properties and used in some disinfectant products

Upstream product

• 14961-34-3 diethyl homophthalate 
• 25705-34-4 2-(2-oxoethyl)benzaldehyde 
• 90535-98-1 (2-hydroxymethyl-phenyl)-acetaldehyde 
• 100613-17-0 1-(2-acetoxy-ethyl)-2-acetoxymethyl-benzene 
• 703-59-3 homophthalic anhydride 
• 4702-34-5 isochroman-1-one 
• 89-51-0 Homophthalic acid 
• 125593-24-0 <2-(2-hydroxyethyl)phenyl>diazomethane 
• 125593-23-9 2-(2-hydroxyethyl)benzaldehyde tosylhydrazone 
• 35050-30-7 2-(2-hydroxyethyl)benzylamine hydrochloride 
• 67-56-1 methanol 
• 95-13-6 1-indene 
• 50-00-0 formaldehyd 
• 6921-34-2 benzylmagnesium chloride 

Downstream Products

• 493-05-0 isochromane 
• 4702-34-5 isochroman-1-one 
• 78317-75-6 1-(2-chloroethyl)-2-chloromethylbenzene 
• 122444-35-3 2-(2-bromomethyl)-phenethyl alcohol 
• 71642-58-5 2-(3,4-dimethoxy-phenethyl)-1,2,3,4-tetrahydro-isoquinoline 
• 81168-16-3 2-<2-(t-Butyldimethylsilyloxy)ethyl>benzenemethanol 
• 136935-27-8 {2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-phenyl}-methanol 
• 13605-95-3 N-benzyl-1,2,3,4-tetrahydroisoquinoline 
• 34818-50-3 isochroman-1-yl acetate 
• 149296-21-9 1-Chloromethyl-2-(2-mesyloxyethyl)benzene 
• 38256-56-3 1-(2-bromo-ethyl)-2-bromomethyl-benzene 
• 4385-35-7 isochroman-3-one 
• 888324-77-4 2-[2-((tert-butyldimethylsilanyloxy)methyl)phenyl]ethanol 
• 942062-87-5 2-[2-((tert-butyldimethylsilanyloxy)methyl)phenyl]acetaldehyde 

Relevant articles and documents

A synthesis method of diol

The present invention belongs to the field of organic synthesis technology, specifically a synthesis method of a diol; the present invention by bis (trimethylsilyl) lithium amino catalytic lactone boronization of lactone to synthesize a variety of structure of the diol compound; specifically, under the bis (trimethylsilyl) amino lithium catalytic system, to a variety of lactone compounds and pinacol borane as raw materials, the preparation of diol compounds; the method of the present invention raw materials are of a wide range of sources or easy to prepare, easy to operate, selective and controllable, high yield, mild conditions, universality wide.

A phosphine-free iron complex-catalyzed synthesis of cycloalkanes: Via the borrowing hydrogen strategy

Herein we report a diaminocyclopentadienone iron tricarbonyl complex catalyzed synthesis of substituted cyclopentane, cyclohexane and cycloheptane compounds using the borrowing hydrogen strategy in the presence of various substituted primary and secondary 1,n diols as alkylating reagents. Deuterium labeling experiments confirm that the diols were the hydride source in this cascade process. This journal is

Synthesis of 1,2-phenylenedimethanols by base-promoted reduction of isobenzofuran-1(3H)-ones with silane

An efficient method for preparation of substituted 1,2-phenylenedimethanols and aliphatic 1,4-diols that are valuable intermediates in organic synthesis, has been developed by the base-promoted reduction of isobenzofuran-1(3H)-ones and γ-lactones with silane under mild conditions. Compared with traditional procedures using stoichiometric amounts of metal hydrides and alkyl reductants, the present method avoids the use of sensitive reagents and is operationally simple and a broad variety of functional groups are tolerated.