63497-88-1

Basic information

• Product Name: Benzamide, 4-amino-N-butyl-3-chloro-5-(trifluoromethyl)-
• CAS NO: 63497-88-1
• Molecular Formula: C12H14ClF3N2O
• Molecular Weight: 294.704
• Mol File: 63497-88-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, 4-amino-N-butyl-3-chloro-5-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-amino-N-butyl-3-chloro-5-(trifluoromethyl)-(63497-88-1)
• EPA Substance Registry System: Benzamide, 4-amino-N-butyl-3-chloro-5-(trifluoromethyl)-(63497-88-1)

Safety Data

• Hazardous Substances Data: 63497-88-1(Hazardous Substances Data)

Upstream product

• 63498-15-7 4-amino-3-chloro-5-trifluoromethyl-benzoyl chloride 

Relevant articles and documents

Amino-benzoic acid amides

Compounds of the formula STR1 wherein (A) WHEN THE AMINO-SUBSTITUENT IS IN THE P-POSITION WITH RESPECT TO THE CARBONYL GROUP, R1 is chlorine in the o-position with respect to the carbonyl group, R2 is hydrogen, and R3 is ethylamino, cyclopentylamino, cyclohexylamino, cycloheptylamino, N-methyl-cyclohexylamino, benzylamino or 1-ethyl-pyrrolidyl-(2)-aminomethyl, or (b) when the amino-substituent is in the o--, m-- or p-position with respect to the carbonyl group, R1 is hydrogen, chlorine or bromine, R2 is trifluoromethyl, nitro or, when R4 is 1-(alkyl of 1 to 3 carbon atoms)-pyrrolidyl or 1-(alkyl of 1 to 3 carbon atoms)-piperidyl, also fluorine, chlorine, bromine or methyl, R3 is (alkyl of 1 to 5 carbon atoms)-amino, (cycloalkyl of 3 to 7 carbon atoms)-amino, benzylamino, quinuclidinyl-amino or --NH--(CH2)n --R4 where R4 is pyridyl, 1-(alkyl of 1 to 3 carbon atoms)-pyrrolidyl, 1-(alkyl of 1 to 3 carbon atoms)-piperidyl or, when n is 2 or 3, also imidazolonyl, pyrrolidino, piperidino or morpholino, and n is 0, 1, 2 or 3, And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as anxiolytics, anticonvulsives, antiemetics and antiulcerogenics.