63537-05-3

Basic information

• Product Name: Benzene, (3-chloro-1-butenyl)-
• CAS NO: 63537-05-3
• Molecular Formula: C10H11Cl
• Molecular Weight: 166.65
• Mol File: 63537-05-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzene, (3-chloro-1-butenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (3-chloro-1-butenyl)-(63537-05-3)
• EPA Substance Registry System: Benzene, (3-chloro-1-butenyl)-(63537-05-3)

Safety Data

• Hazardous Substances Data: 63537-05-3(Hazardous Substances Data)

Upstream product

• 122-57-6 1-Phenylbut-1-en-3-one 
• 17488-65-2 4-phenylbut-3-en-2-ol 
• 36004-04-3 ethyl (E)-1-phenylbut-1-en-3-ol 
• 14371-10-9 (E)-3-phenylpropenal 
• 1896-62-4 (E)-benzalacetone 
• 52755-39-2 (2E)-1-phenylbut-2-en-1-ol 
• 82045-04-3 (rac)-(E)-2-acetoxy-4-phenylbut-3-ene 
• 32644-22-7 1-methyl-3-phenylallene 

Downstream Products

• 15325-63-0 (E)-3-methyl-1-phenyl-1-pentene 
• 78087-01-1 (S,E)-hex-4-en-3-ylbenzene 
• 78086-99-4 (R,Z)-hex-4-en-3-ylbenzene 
• 78087-00-0 (R,E)-hex-4-en-3-ylbenzene 
• 1219117-70-0 C₁₄H₂₁O₃PS 
• 107847-42-7 C₂₀H₂₂ 
• 107847-43-8 C₂₀H₂₂ 
• 92776-47-1 (+/-)-4-phenyl-oct-2Ξ-ene 
• 112528-98-0 (E)-(±)-2-methyl-4-phenylbut-3-enenitrile 
• 1104996-91-9 (E)-1-methyl-4-[1-methyl-3-phenyl-2-propen-1-yl]benzene 
• 1380425-95-5 (Z)-1-methyl-4-[1-methyl-3-phenyl-2-propen-1-yl]benzene 
• 1380425-96-6 (Z)-1-methoxy-4-[1-methyl-3-phenyl-2-propen-1-yl]benzene 
• 7302-00-3 (E)-1,3-diphenyl-1-butene 
• 7302-01-4 (Z)-(3-methyl-1-propene-1,3-diyl)dibenzene 

Relevant articles and documents

METHOD OF CONVERTING ALCOHOL TO HALIDE

The present invention relates to a method of converting an alcohol into a corresponding halide. This method comprises reacting the alcohol with an optionally substituted aromatic carboxylic acid halide in presence of an N-substituted formamide to replace a hydroxyl group of the alcohol by a halogen atom. The present invention also relates to a method of converting an alcohol into a corresponding substitution product. The second method comprises: (a) performing the method of the invention of converting an alcohol into the corresponding halide; and (b) reacting the corresponding halide with a nucleophile to convert the halide into the nucleophilic substitution product.

Copper-catalyzed nucleophilic trifluoromethylation of allylic halides: A simple approach to allylic trifluoromethylation

Trifluoromethylation: The treatment of allylic halides with trifluoromethyltrimethylsilane in the presence of a catalytic amount of copper(I) thiophene-2-carboxylate (CuTC) gives the corresponding allylic trifluoromethylation products in good to high yields and with complete regioselectivity (see scheme). The use of THF as a solvent is crucial for obtaining good yields of product.

Identification of a valuable kinetic process in copper-catalyzed asymmetric allylic alkylation

Copper bottomed: The application of a previously described process of dynamic kinetic asymmetric transformation to acyclic substrates allowed the identification of a relevant kinetic process in the title reaction (see scheme; CuTC= copper(I) thiophencarboxylate, Naphth= naphthyl). The optimization of the reaction conditions and generality of the method, as well as mechanistic considerations are disclosed.