635683-12-4

Basic information

• Product Name: Acetonitrile, [methyl(3-methylphenyl)amino]- (9CI)
• Synonyms: Acetonitrile, [methyl(3-methylphenyl)amino]- (9CI);2-(Methyl(M-tolyl)aMino)acetonitrile;N-Methyl-N-(3-methylphenyl)aminoacetonitrile
• CAS NO: 635683-12-4
• Molecular Formula: C10H12N2
• Molecular Weight: 160.21568
• Product Categories: AMINETERTIARY
• Mol File: 635683-12-4.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 158℃ (9 Torr)
• Flash Point: 124.119 °C
• Appearance: /
• Density: 1.043 g/cm³
• PKA: 1.81±0.50(Predicted)
• CAS DataBase Reference: Acetonitrile, [methyl(3-methylphenyl)amino]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Acetonitrile, [methyl(3-methylphenyl)amino]- (9CI)(635683-12-4)
• EPA Substance Registry System: Acetonitrile, [methyl(3-methylphenyl)amino]- (9CI)(635683-12-4)

Safety Data

• Hazardous Substances Data: 635683-12-4(Hazardous Substances Data)

Usage

General Description

Acetonitrile, [methyl(3-methylphenyl)amino]- (9CI) is a chemical compound with the molecular formula C9H10N2. It is also known by its CAS number 6722-48-5. Acetonitrile, [methyl(3-methylphenyl)amino]- (9CI) is a derivative of acetonitrile and contains a methyl group attached to the nitrogen atom and a 3-methylphenyl amino group attached to the carbon atom. It is commonly used as a solvent in various chemical reactions and processes, and it also has applications in the pharmaceutical and agricultural industries. Acetonitrile, [methyl(3-methylphenyl)amino]- (9CI) may also be used in the synthesis of other organic compounds. As with any chemical substance, safe handling and proper usage protocols should be followed to prevent any potential health or environmental hazards.

Upstream product

• 121-72-2 N,N-dimethyl-m-toluidine 
• 624-75-9 iodoacetonitrile 
• 143-33-9 sodium cyanide 
• 773837-37-9 sodium cyanide 
• 7677-24-9 trimethylsilyl cyanide 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 623-49-4 ethyl cyanoformate 
• 372-09-8 cyanoacetic acid 
• 696-44-6 N-methyl-m-toluidine 
• 67-56-1 methanol 
• 108-44-1 1-amino-3-methylbenzene 
• 613-90-1 benzoyl cyanide 
• 78-67-1 2,2'-azobis(isobutyronitrile) 
• 6011-14-9 2-aminoacetonitrile hydrochloride 

Relevant articles and documents

Method for preparing alpha-aminonitrile and product and application thereof

The invention discloses a method for preparing alpha-aminonitrile, which comprises the following steps: by using tertiary amine and benzoyl cyanide as reactants, carrying out visible light irradiationin an organic solvent under the condition of oxygen or

Iron-catalyzed reductive strecker reaction

Strecker reaction is widely applied for the synthesis of amino acids from aldehydes, amines and cyanides. Herein, we report the FeI2-catalyzed reductive Strecker type reaction of formamides instead of aldehydes to produce amino acetonitriles. The challenging capture of carbinolamine intermediates by CN? was achieved via Fe catalysis. This approach afforded better yields than the use of Ir- or Rh-catalysts. The application ability of this methodology is demonstrated by 1) one-pot construction of (13C labeled) complex molecules from CO2 via amino acetonitrile intermediates and 2) convenient production of homologated carboxylic acids from aldehydes.

Electron Donor-Acceptor Complex-Initiated Photochemical Cyanation for the Preparation of α-Amino Nitriles

An electron donor-acceptor complex-initiated α-cyanation of tertiary amines has been described. The reaction protocol provides a novel method to synthesize various α-amino nitriles under mild conditions. The reaction can proceed smoothly without the presence of photocatalysts and transition metal catalysts, and either oxidants are unnecessary or O2 is the only oxidant. The practicality of this method is showcased not only by the late-stage functionalization of natural alkaloid derivatives and pharmaceutical intermediate, but also by the applicability of a stop-flow microtubing reactor.