63604-98-8

Basic information

• Product Name: Phenol, 3,5-bis(phenylmethoxy)-
• Synonyms: bis-O-benzyl phloroglucinol;phloroglucinol dibenzyl ether;3,5-dibenzyloxyphenol;1,3-di-O-benzylphloroglucinol;3,5-di-O-benzyl phloroglucinol
• CAS NO: 63604-98-8
• Molecular Formula: C20H18O3
• Molecular Weight: 306.361
• Mol File: 63604-98-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 94 °C
• Boiling Point: 505.1±40.0 °C(Predicted)
• Density: 1.190±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Phenol, 3,5-bis(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 3,5-bis(phenylmethoxy)-(63604-98-8)
• EPA Substance Registry System: Phenol, 3,5-bis(phenylmethoxy)-(63604-98-8)

Safety Data

• Hazardous Substances Data: 63604-98-8(Hazardous Substances Data)

Usage

Uses

3,?5-?Bis(phenylmethoxy)?phenol is used as a reagent for Friedel-?Crafts propargylic alkylation for phenol structures.1

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 2999-40-8 1,3,5-triacetoxybenzene 
• 3147-39-5 methyl 2,4,6-trihydroxybenzoate 
• 3900-81-0 phloroglucinol monobenzenesulfonate 
• 3840-04-8 1,3,5-tris<(benzenesulfonyl)oxy>benzene 
• 59434-20-7 1,3,5-tri-O-benzylphloroglucinol 
• 78596-73-3 phloroglucinol dibenzyl ether monobenzenesulfonate 
• 77376-62-6 methyl 2,4-dibenzyloxy-6-hydroxybenzoate 

Downstream Products

• 141039-10-3 4-benzyloxy-7-<(3,5-dibenzyloxyphenyl)oxy>methyl-7-cyano-3-methoxybicyclo<4.2.0>octa-1,3,5-triene 
• 78596-76-6 3-acetoxy-3a-bromo-4,6-bis(benzyloxy)-2,3,3a,8a-tetrahydrofuro<2,3-b>benzofuran 
• 63604-97-7 C₃₈H₄₄Br₂O₆ 
• 65658-30-2 2-Chlor-3,5-dibenzyloxyphenol 
• 65658-29-9 4-Chlor-3,5-dibenzyloxyphenol 
• 188579-05-7 3,5-Bis-benzyloxy-2-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-phenol 
• 6743-86-8 1,3-diacetoxy-5-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)benzene 
• 216968-14-8 3-[3,5-bis(benzyloxy)phenoxy]propanol 
• 332386-61-5 (E)-3-[2,4-bis(benzyloxy)-6-hydroxyphenyl]-1-[3,4,5-tris(benzyloxy)phenyl]-propene 
• 461055-42-5 5-bromopentyl-3,5-dibenzyl phloroglucinol 
• 461055-43-6 C₈₁H₈₄O₁₂ 
• 773859-52-2 (E)-3-[2,4-bis(benzyloxy)-6-hydroxyphenyl]-1-(4-benzyloxyphenyl)propene 
• 768387-11-7 3,4,5-Tris-dodecyloxy-benzoic acid 4-(3,5-dihydroxy-phenoxycarbonyl)-phenyl ester 
• 901125-39-1 (+)-(2R)-5,7-bis(benzyloxy)-2-[3',5'-bis(benzyloxy)-4'-methoxyphenyl]chroman-3-one 

Relevant articles and documents

Enantio selective synthesis of new phenylpropanoid: Isolated from Walsura trifoliata

A new phenylpropanoid containing flavon-3-ol has been isolated from the leaves of traditional medicinal plant, Walsura trifoliata. The structure of the compound was established on the basis of spectroscopic evidence [2D NMR, HREIMS] and by its alternative

Collective Syntheses of 2-(3-Methylbenzofuran-2-yl)phenol-Derived Natural Products by a Cascade [3,3]-Sigmatropic Rearrangement/Aromatization Strategy

A cascade [3,3]-sigmatropic rearrangement/aromatization strategy to the synthesis of 2-(3-methylbenzofuran-2-yl)phenol derivatives was developed and applied to the collective syntheses of seven 2-arylbenzofuran-containing natural products, namely glycybenzofuran, glycyuralin E, lespedezol A1, puerariafuran, 7,2′,4′-trihydroxy-3-benzofurancarboxylic acid, coumestrol, and 4′-O-methylcoumestrol. Among them, the total syntheses of glycybenzofuran, glycyuralin E, puerariafuran, 7,2′,4′-trihydroxy-3-benzofurancarboxylic acid, and 4′-O-methylcoumestrol were reported for the first time. The practicality of this novel strategy in preparation of the key intermediates was demonstrated by performing the reaction on gram scale and by synthesizing a series of natural products with 2-(3-methylbenzofuran-2-yl)phenol scaffolds in a common strategy.

Synthesis of catechin and epicatechin conjugates

The present invention relates generally to catechin and epicatechin conjugates of formula (I). For example, a chemical synthesis process for the preparation of catechin and epi-catechin compounds, in particular of catechin and epi-catechin conjugates is disclosed. A further aspect of the invention pertains to new catechin and epi-catechin conjugate compounds.