63684-99-1 Usage
General Description
1-(3,4-Dichlorophenyl)-5-mercapto-1H-tetrazole is a chemical compound with the molecular formula C7H4Cl2N4S. It is a tetrazole derivative with a substituted phenyl ring and a mercapto group. 1-(3,4-DICHLOROPHENYL)-5-MERCAPTO-1H-TETRAZOLE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has been studied for its potential as a therapeutic agent for various diseases, including cancer and cardiovascular disorders. Additionally, it is also used in the field of material science as a building block for the creation of novel polymeric materials. The compound's unique chemical structure and potential applications make it an important molecule in the realm of drug discovery and materials research.
Check Digit Verification of cas no
The CAS Registry Mumber 63684-99-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,6,8 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63684-99:
(7*6)+(6*3)+(5*6)+(4*8)+(3*4)+(2*9)+(1*9)=161
161 % 10 = 1
So 63684-99-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4Cl2N4S/c8-5-2-1-4(3-6(5)9)13-7(14)10-11-12-13/h1-3H,(H,10,12,14)
63684-99-1Relevant articles and documents
Tetrazole thioacetanilides: Potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant
Muraglia, Ester,Kinzel, Olaf D.,Laufer, Ralph,Miller, Michael D.,Moyer, Gregory,Munshi, Vandna,Orvieto, Federica,Palumbi, Maria Cecilia,Pescatore, Giovanna,Rowley, Michael,Williams, Peter D.,Summa, Vincenzo
, p. 2748 - 2752 (2007/10/03)
A series of aryltetrazolylacetanilides was synthesized and evaluated as HIV-1 non-nucleoside reverse transcriptase inhibitors on wild-type virus and on the clinically relevant K103N mutant strain. Extensive SAR investigation led to potent compounds, with nanomolar activity on K103N, and orally bioavailable in rats.
