639458-43-8

Basic information

• Product Name: (S)-1-Boc-2-(2-Oxoethyl)Piperidine
• Synonyms: (S)-1-Boc-2-(2-Oxoethyl)Piperidine;1-Piperidinecarboxylic acid, 2-(2-oxoethyl)-, 1,1-diMethylethyl ester, (2S)-
• CAS NO: 639458-43-8
• Molecular Formula: C₁₂H₂₁NO₃
• Molecular Weight: 227.30004
• Mol File: 639458-43-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1-Boc-2-(2-Oxoethyl)Piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Boc-2-(2-Oxoethyl)Piperidine(639458-43-8)
• EPA Substance Registry System: (S)-1-Boc-2-(2-Oxoethyl)Piperidine(639458-43-8)

Safety Data

• Hazardous Substances Data: 639458-43-8(Hazardous Substances Data)

Usage

Description

(S)-1-Boc-2-(2-Oxoethyl)Piperidine, also known as (S)-N-Boc-2-piperidone, is a chemical compound belonging to the class of piperidines. It is characterized by its white to off-white solid appearance and a molecular formula of C13H23NO3, with a molecular weight of 241.33 g/mol. (S)-1-Boc-2-(2-Oxoethyl)Piperidine is widely recognized for its role as an intermediate in the production of pharmaceuticals and agrochemicals, making it a valuable asset in the field of organic chemistry and pharmaceutical research.

Uses

Used in Pharmaceutical Industry:
(S)-1-Boc-2-(2-Oxoethyl)Piperidine is used as an intermediate for the synthesis of various pharmaceutical compounds. Its application is primarily due to its ability to serve as a building block for complex molecules, which is crucial in drug discovery and development. The presence of the Boc (tert-butyloxycarbonyl) group, a common protecting group for amines in organic synthesis, further enhances its versatility in the synthesis of a wide range of compounds.
Used in Agrochemical Industry:
In the agrochemical industry, (S)-1-Boc-2-(2-Oxoethyl)Piperidine is utilized as an intermediate for the production of various agrochemicals. Its role in this industry is attributed to its capacity to contribute to the development of new and improved agrochemical products, thereby supporting agricultural advancements and crop protection.
Overall, (S)-1-Boc-2-(2-Oxoethyl)Piperidine plays a significant role in both the pharmaceutical and agrochemical industries, primarily due to its versatility as a synthetic intermediate and its potential applications in drug discovery, development, and the creation of new agrochemical products.

Upstream product

• 199942-74-0 (S)-2-(2-hydroxy-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 118811-03-3 tert-butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate 
• 639458-49-4 (S)-2-(2-acetoxy-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 821-77-2 5-hexenylazide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 2695-47-8 6-Bromo-1-hexene 
• 202926-14-5 tert-butyl hex-5-en-1-ylcarbamate 
• 1484-84-0 2(RS)-(2-hydroxyethyl)piperidine 
• 1007600-14-7 N-acetyl-L-leucine (S)-2-piperidineethanol 
• 26250-84-0 (S)-(-)-1-(tert-butoxycarbonyl)-2-piperidinecarboxylic acid 
• 134441-93-3 tert-butyl (2S)-2-(hydroxymethyl)piperidine-1-carboxylate 
• 150521-32-7 (S)-1-N-Boc-piperidine-2-al 
• 159898-10-9 (S)-2-{1-[(tert-butoxy)carbonyl]piperidin-2-yl}acetic acid 

Downstream Products

• 311772-70-0 (R)-2-((R)-2-hydroxy-2-phenylethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 639458-44-9 (S,S)-2-(2-hydroxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 67008-23-5 (2R)-2-((2R)-2-hydroxy-2-phenylethyl)-1-methylpiperidine 
• 497-88-1 (-)-sedamine 
• 639458-45-0 2-(2-hydroxy-2-phenyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1362119-77-4 C₃₂H₅₂N₂O₇S 
• 1362120-03-3 C₃₂H₅₂N₂O₇S 
• 1362120-23-7 C₁₉H₂₇NO₄S 
• 1362120-00-0 C₁₉H₂₇NO₄S 
• 1362120-17-9 C₁₉H₂₆ClNO₄ 
• 1362119-79-6 C₂₀H₃₁NO₄S 
• 1362120-25-9 C₂₀H₃₁NO₄S 
• 1362120-15-7 C₃₂H₅₀N₂O₇S 
• 199942-74-0 (S)-2-(2-hydroxy-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

(QUINOLINE OR ISOQUINOLINE)SULFONAMIDES OF CYCLIC AMINES AS ANTIPSYCHOTIC DRUGS

The invention relates to compounds of general formula (I) wherein: one of A1 and A2 represents a nitrogen atom and the other a carbon atom optionally substituted by halogen; the wave line between the sulfonamido moiety and B/C rings represents a single bond linking the sulfur atom to a non-bridgehead carbon atom, with the proviso that the part of ring C being detached by the dashed broken line is unsubstituted; n represents an integer from 0 to 3; Y represents a nitrogen or carbon atom; Z represents a 5-6 membered aromatic/ heteroaromatic ring optionally fused with a further aromatic or non- aromatic 5-6 membered heterocycle, the condensed ring system being linked via a non-bridgehead carbon atom. The compounds display high affinity for the D2, D3, 5-HT1A, 5-HT2A- 5-HT6 and 5-HT7 receptors and are useful for the treatment of psychotropic diseases or disorders associated with disturbances of the dopaminergic/ serotoninergic systems such as schizophrenia and autism.

Enantioselective approach to quinolizidines: Total synthesis of cermizine D and formal syntheses of senepodine G and cermizine C

The formal syntheses of C5-epi-senepodine G and C 5-epi-cermizine C have been accomplished through a novel diastereoselective, intramolecular amide Michael addition process. The total synthesis of cermizine D has been achieved throug

Expedient enantioselective synthesis of cermizine D

An efficient enantioselective synthesis of cermizine D has been developed that exploits the use of a common intermediate to access over 85% of the carbon backbone. Key steps include an organocatalyzed heteroatom Michael addition, a diastereoselective alky