64030-44-0Relevant articles and documents
Modular synthesis of new bicyclic carbene precursors
Li, Jie,Yao, Jiaqi,He, Weiping,Yang, Fan,Liu, Xiaoming
, p. 951 - 954 (2019/11/22)
A series of new N-heterocyclic carbene (NHC) precursors, containing bicyclic pyrrolo[1,2-c]imidazole framework, were prepared from N-(tert-butoxycarbonyl)-L-proline (1-Boc-L-proline). The sequential attachment of nitrogen nucleophiles and subsequent ring
Transfer hydrogenation reactions catalyzed by chiral half-sandwich Ruthenium complexes derived from Proline
Pandia Kumar, Arun Kumar,Samuelson, Ashoka G
, p. 1405 - 1415 (2016/09/19)
Chiral ruthenium half-sandwich complexes were prepared using a chelating diamine made from proline with a phenyl, ethyl, or benzyl group, instead of hydrogen on one of the coordinating arms. Three of these complexes were obtained as single diastereoisomers and their configuration identified by X-ray crystallography. The complexes are recyclable catalysts for the reduction of ketones to chiral alcohols in water. A ruthenium hydride species is identified as the active species by NMR spectroscopy and isotopic labelling experiments. Maximum enantio-selectivity was attained when a phenyl group was directly attached to the primary amine on the diamine ligand derived from proline. [Figure not available: see fulltext.]
Chiral amine catalyzed enantio- and diastereoselective Michael reaction in brine
Singh, Sarbjit,Chimni, Swapandeep Singh
, p. 1068 - 1079 (2012/11/06)
Simple pyrrolidine-based chiral amines were synthesized and used for the Michael addition of different ketones to a variety of nitro-olefins in brine. The effect of different surfactants and acids on the yields and stereochemical outcome of the Michael ad