64050-53-9

Basic information

• Product Name: Phosphoric acid diethyl(1-naphtylmethyl) ester
• Synonyms: Diethyl(1-naphtylmethyl) =phosphate;Phosphoric acid diethyl(1-naphtylmethyl) ester
• CAS NO: 64050-53-9
• Molecular Formula: C₁₅H₁₉O₄P
• Molecular Weight: 294.2827
• Mol File: 64050-53-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 411.9°Cat760mmHg
• Flash Point: 216.3°C
• Appearance: /
• Density: 1.181g/cm³
• Vapor Pressure: 1.29E-06mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: Phosphoric acid diethyl(1-naphtylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphoric acid diethyl(1-naphtylmethyl) ester(64050-53-9)
• EPA Substance Registry System: Phosphoric acid diethyl(1-naphtylmethyl) ester(64050-53-9)

Safety Data

• Hazardous Substances Data: 64050-53-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H19O4P/c1-3-17-20(16,18-4-2)19-12-14-10-7-9-13-8-5-6-11-15(13)14/h5-11H,3-4,12H2,1-2H3

Upstream product

• 4780-79-4 1-naphthalene methanol 
• 814-49-3 diethyl chlorophosphate 
• 66-77-3 1-naphthaldehyde 
• 762-04-9 phosphonic acid diethyl ester 
• 1090-21-7 diethyl hydroxy(naphth-1-yl)methylphosphonate 

Downstream Products

• 5903-23-1 1-(methoxymethyl)naphthalene 
• 90-12-0 1-Methylnaphthalene 
• 19351-91-8 N-(naphthalene-1-ylmethyl)acetamide 
• 611-45-0 1-Benzyl-naphthalene 
• 607-50-1 1,1'-dinaphthylmethane 

Relevant articles and documents

Formation of new phosphates from aldehydes by a DBU-catalysed phospha-brook rearrangement in a polar solvent

Addition of dialkylphosphites to aromatic aldehydes (Pudovik reaction) by treatment with a base results in two different possible reaction pathways depending on the solvent used. Apolar solvents give the normal Pudovik adduct, whereas the use of DBU in a polar solvent allows the formation of a phosphate ester via phospha-Brook rearrangement of the intermediate hydroxyphosphonate. Georg Thieme Verlag Stuttgart.

Synthesis of diarylmethanes through palladium-catalyzed coupling of benzylic phosphates with arylsilanes

An efficient approach to the benzylation of arenes has been developed. The reactions described provide straightforward access to diarylmethanes through Pd-catalyzed coupling of benzylic phosphates with arylsilanes in good to excellent yields. The reaction tolerates a wide range of functionalities such as halide, alkoxyl, and nitro groups.

Suzuki-Miyaura cross-coupling of benzylic phosphates with arylboronic acids

(Chemical Equation Presented) Suzuki-Miyaura cross-coupling of benzylic phosphates with arylboronic acids was investigated. Optimum conditions employed the simple catalytic system of palladium(II) acetate (1 mol %) and triphenylphosphine (4 mol %) with either potassium phosphate or potassium carbonate as the base and toluene as the solvent at 90°C. Using the developed conditions, a series of structurally diverse diarylmethanes were prepared.