644989-76-4

Basic information

• Product Name: [2-(3,3-dimethyl-2-oxo-azetidin-1-yl)-1-(4-methoxy-benzyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
• Synonyms: [2-(3,3-dimethyl-2-oxo-azetidin-1-yl)-1-(4-methoxy-benzyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 644989-76-4
• Molecular Weight: 376.453
• Mol File: 644989-76-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-(3,3-dimethyl-2-oxo-azetidin-1-yl)-1-(4-methoxy-benzyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(3,3-dimethyl-2-oxo-azetidin-1-yl)-1-(4-methoxy-benzyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(644989-76-4)
• EPA Substance Registry System: [2-(3,3-dimethyl-2-oxo-azetidin-1-yl)-1-(4-methoxy-benzyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester(644989-76-4)

Safety Data

• Hazardous Substances Data: 644989-76-4(Hazardous Substances Data)

Upstream product

• 7486-91-1 3,3-dimethyl-2-azetidinone 
• 68856-96-2 N-(tert-butoxycarbonyl)-O-methyl-D-tyrosine 

Downstream Products

• 644989-77-5 (E)-(3S,10R,16S)-3-Isobutyl-10-(4-methoxy-benzyl)-6,6-dimethyl-16-((E)-(R)-1-methyl-3-phenyl-allyl)-1,4-dioxa-8,11-diaza-cyclohexadec-13-ene-2,5,9,12-tetraone 
• 644989-79-7 (3E)-1-[(2E)-3-(N-{(1R)-2-(3,3-dimethyl-2-oxoazetidin-1-yl)-1-[(4-methoxyphenyl)methyl]-2-oxoethyl}carbamoyl)prop-2-enyl]-(1S,2R)-2-methyl-4-phenylbut-3-enyl (2S)-2-hydroxy-4-methylpentanoate 

Relevant articles and documents

Synthesis of Cryptophycins via an N-Acyl-β-lactam Macrolactonization

An efficient and concise approach to the synthesis of the macrolide core of the cryptophycins has been developed. A novel macrolactonization utilizing a reactive acyl-β-lactam intermediate incorporates the β-amino acid moiety within the 16-membered macrol