64991-57-7

Basic information

• Product Name: Boc-Cys(Dppm)-Ala-OPic
• Synonyms: Boc-Cys(Dppm)-Ala-OPic
• CAS NO: 64991-57-7
• Molecular Weight: 626.777
• Mol File: 64991-57-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Boc-Cys(Dppm)-Ala-OPic(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Cys(Dppm)-Ala-OPic(64991-57-7)
• EPA Substance Registry System: Boc-Cys(Dppm)-Ala-OPic(64991-57-7)

Safety Data

• Hazardous Substances Data: 64991-57-7(Hazardous Substances Data)

Upstream product

• 62982-14-3 N-t-butoxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine dicyclohexylammonium salt 
• 62982-12-1 S-(diphenyl-4-pyridylmethyl)-L-cysteine 
• 77422-40-3 tert-butyloxycarbonylalanyl-4-pyridylmethylester 
• 14548-46-0 4-Benzoylpyridine 
• 1620-30-0 diphenyl(pyridin-4-yl)methanol 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 586-95-8 pyridine-4-methanol 
• 76369-75-0 L-alanine 4-picolyl ester dihydrobromide 
• 62982-13-2 N-t-butoxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteine 
• 64991-56-6 L-alanine 4-picolyl ester 

Downstream Products

• 62982-19-8 Boc-Ile-Ala-Cys(Dppm)-Ala-Cys(Dppm)-Ala-OPic 
• 62982-18-7 S-(diphenyl-4-pyridylmethyl)-L-cysteinyl-L-alanine 
• 64991-58-8 N-t-butoxycarbonyl-S-(diphenyl-4-pyridylmethyl)-L-cysteinyl-L-alanine 

Relevant articles and documents

Amino-acids and Peptides. Part 45. The Protection of the Thiol Function of Cysteine and the Imidazole-N of Histidine by the Diphenyl-4-pyridylmethyl Group

S-(Diphenyl-4-pyridylmethyl)-L-cysteine (1) and its derivatives (2)-(7) have been prepared and used in peptide synthesis.In contrast to the analogous S-trityl group, this protection is stable in acid but it is cleaved readily by zinc-acetic acid, by mercury(II) acetate, by iodine, and by electrolytic reduction.N(Im)-Diphenyl-4-pyridylmethyl-L-histidine derivatives (9)-(13) are also reported; the protecting group is again stable to acid but cleaved by hydrogenolysis, by zinc-acetic acid, and by electrolytic reduction, and it has been used in the synthesis of L-histidyl-L-leucine, -L-phenylalanine, and -glycine.