65043-22-3 Usage
Description
Indeloxazine hydrochloride is a nootropic compound that is primarily indicated for the treatment of senile dementia. It has been observed to enhance brain energy metabolism and monoamine content in animal models, and its protective effect on ischemia-induced amnesia is supported by the prolonged step-through latency in passive avoidance tests.
Uses
Used in Pharmaceutical Industry:
Indeloxazine hydrochloride is used as a therapeutic agent for the treatment of senile dementia, aiming to improve cognitive function and alleviate symptoms associated with the condition.
Used as an Antidepressant:
Indeloxazine hydrochloride is also utilized as an antidepressant, potentially providing relief from depressive symptoms and improving overall mood and well-being.
Originator
Yamanouchi (Japan)
Metabolic pathway
After oral administration of indeloxazine hydrochloride
to rats, two conjugates, which are labile to a-
glucosidase hydrolysis but refractory to b-glucosidase,
are isolated from the urine and identified as a-D-
glucopyranosides of trans-4-(2-morpholinylmethoxy)-
1,2-indandiol and trans-6-[[(1,2-dihydroxy-4-
indanyl)oxy]-methyl]-3-morpholinone.
Check Digit Verification of cas no
The CAS Registry Mumber 65043-22-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,0,4 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 65043-22:
(7*6)+(6*5)+(5*0)+(4*4)+(3*3)+(2*2)+(1*2)=103
103 % 10 = 3
So 65043-22-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H17NO2.ClH/c1-3-11-4-2-6-14(13(11)5-1)17-10-12-9-15-7-8-16-12;/h1-4,6,12,15H,5,7-10H2;1H